EEG tracings were analysed in 100 children of 58 fathers with epilepsy. A group of children aged up to 18 years was isolated and in 40 of them serial EEG investigations were carried out during 4-5 years. In this group abnormal tracings were found in 51% of cases, with seizure activity in 31%. In five children (5%) epilepsy was diagnosed. Seizure activity was significantly more frequent in girls than in boys (42.8% vs 19.6%). Seizure activity occurred with similar frequency in children born before or after manifestation of the disease in the father (30.1% and 31.9%). The observation of evolution of seizure activity during 4-5 years suggests that the greatest penetration is at the age of 4-7 years (52.6%) and then it decreases gradually. Non-seizure pathological activity with features of bioelectric immaturity was observed most frequently in the youngest children aged 1-3 years, especially in boys. The evolution of these changes was bidirectional: in most cases the tracings became normal within 4-5 years, in a lower number of cases seizure activity appeared.
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