This study explores the impact of the 'pre-intervention effects' of a community-based intervention. This refers to participatory research processes and parallel publicity in the media on changes in alcohol use and relevant mechanisms (rules and norms about alcohol, accessibility of alcohol in a formal setting) among adolescents before any intervention is implemented. The aim was to investigate the contribution of these processes (i.e., pre-intervention effects) to changes in intervention-targeted factors before any actual intervention was implemented. In a quasi-experimental study, data were collected twice by means of self-report among adolescents living in two municipalities (control and experimental condition). A regression analysis showed negative pre-intervention main effects on adolescents' perceived accessibility of alcohol in a formal setting. Moreover, among adolescents aged 15 years and older, the normative decline in strictness of rules and norms was less steep in the experimental condition compared to the control condition. Additionally, adolescents aged 14 years and younger in the experimental condition reported more weekly drinking compared to their peers in the control condition. No differential effects across gender were found. To conclude, applying a co-creational approach in the development of an intervention not only contributes to more effective interventions in the end, but the involvement of and discussions in the community when planning the intervention contribute to changes in targeted factors. This implies that public discussions about the development of intervention strategies should be considered as an essential feature of co-creation in community-based interventions.
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http://dx.doi.org/10.3390/ijerph18168823 | DOI Listing |
Environ Sci Technol
January 2025
Department of Civil and Environmental Engineering, University of Alberta, Edmonton, Alberta T6G 1H9, Canada.
The ubiquitous distribution of microplastics (MPs) in aquatic environments is linked to their transport in rivers and streams. However, the specific mechanism of bedload microplastic (MP) transport, notably their stochastic behaviors, remains an underexplored area. To investigate this, particle tracking velocimetry was employed to examine the continuous near-bed movements of four types of MPs under nine setups with different experimental conditions in a laboratory flume, with an emphasis on their streamwise transport.
View Article and Find Full Text PDFACS Pharmacol Transl Sci
January 2025
Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmacy, The Chinese University of Hong Kong, Shatin 999077, Hong Kong SAR, P. R. China.
Erythroferrone (ERFE) has emerged as a potential biomarker for the erythropoiesis response following recombinant human erythropoietin (rHuEPO) treatment. While the association between ERFE and hemoglobin (HGB) response to rHuEPO is well-established in nonanemic conditions, such correlation and ERFE kinetics in anemic states remain unclear. We employed two rat models of anemia, chronic kidney disease (CKD) anemia and chemotherapy-induced anemia (CIA), to determine ERFE kinetics and its correlation with HGB responses after rHuEPO administration.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Chemical Engineering, School of Chemical and Materials Engineering (SCME), National University of Sciences & Technology (NUST), Sector H-12, Islamabad, 44000, Pakistan.
This study examines the viability of using graphitic-Carbon Nitride (g-CN) nanomaterial as shale stabilizer drilling fluid additive having applications in the oil and gas wells drilling. Shale stability is important especially when drilling horizontal and extended reach wells with water-based muds (WBM) to tap unconventional reservoirs namely shale oil and shale gas. For this study, the g-CN nanomaterial was produced by melamine pyrolysis, and characterized by X-Ray Diffraction, Scanning Electron Microscopy and Fourier Transform Infrared spectroscopy techniques.
View Article and Find Full Text PDFHeliyon
July 2024
School of Physics, Changchun University of Science and Technology, Changchun, 130022, China.
To analyze the motion laws of a magnetic and elastic coupling system under the influence of various factors, this paper proposes a magnetic coupling pendulum based on spring pieces and magnets-a magnetic-mechanical oscillator. By fixing spring pieces onto two non-magnetic bases and attaching magnets to their upper ends, which repel each other, the potential energy during oscillation is expanded using Fourier series. Subsequently, Lagrange equations are solved to study the effects of the first two terms of potential energy.
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