A Health Risk Assessment of Lead and Other Metals in Pharmaceutical Herbal Products and Dietary Supplements Containing in the Mexico City Metropolitan Area.

Int J Environ Res Public Health

Mucosal Immunity Laboratory, Research and Graduate Section, Instituto Politécnico Nacional, Superior School of Medicine, Plan de San Luis Esq. Salvador Díaz Mirón s/n, C.P., Mexico City 11340, Mexico.

Published: August 2021

The use of the medicinal plant has increased worldwide. However, is capable of assimilating both essential and toxic metals, and the ingestion of contaminated products can cause damage to health. The aim of this study was to investigate the safety of manganese (Mn), copper (Cu), lead (Pb), arsenic (As), and cadmium (Cd) in 26 items containing (pharmaceutical herbal products, dietary supplements, and traditional herbal remedies) purchased in the metropolitan area of Mexico City. Metal analysis was performed using a graphite furnace atomic absorption spectrometer. All of the products were contaminated with Pb, 54% of them with As, and 81% with Cd. The lowest values of Pb, As, and Cd were detected in pharmaceutical herbal products > dietary supplements > traditional herbal remedies. The daily intake dose (DID) of pharmaceutical herbal products was within the established limits for the five metals. Dietary supplements and traditional herbal remedies exceeded the DID limits for Pb. The hazard quotients estimation and non-carcinogenic cumulative hazard estimation index for Mn, As, and Cd indicated no human health risk. Our results suggest that products containing for sale in Mexico are not a health risk.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391129PMC
http://dx.doi.org/10.3390/ijerph18168285DOI Listing

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