This review summarizes the current state-of-the-art procedures in terms of the preparation of -arylindoles. After a short introduction, the transition-metal-free procedures available for the -arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed -arylation of indoles are both discussed. In the next section, copper-catalyzed procedures for the -arylation of indoles are described. The final section focuses on recent findings in the field of biologically active -arylindoles.
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| http://dx.doi.org/10.3390/molecules26165079 | DOI Listing |
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