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Value of F-PSMA-PET/MRI for Assessment of Recurring Ranula. | LitMetric

Value of F-PSMA-PET/MRI for Assessment of Recurring Ranula.

Diagnostics (Basel)

Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Eberhard Karls Universität Tübingen, Hoppe-Seyler-Straße 3, 72076 Tuebingen, Germany.

Published: August 2021

AI Article Synopsis

  • - A 6-year-old patient had a suspected recurrence of a plunging ranula after previously undergoing surgery to remove left submandibular and sublingual glands.
  • - To improve diagnostic accuracy, a PET/MRI scan was performed using a specific radiotracer, revealing a diminishing seroma but no signs of persistent glandular tissue.
  • - The results indicated no relapse of the plunging ranula, leading to a conservative treatment approach instead of further surgery, showcasing the PET/MRI's effectiveness in informing surgical decisions.

Article Abstract

We report the case of a 6-year-old patient with suspected recurrence of a plunging ranula in clinical and ultrasonographic examination. Surgical resection of the left submandibular and sublingual glands had already been performed. Since persistent glandular tissue could not be excluded with certainty via MRI, we expanded diagnostics by performing a PET/MRI using a head and neck imaging protocol and the radiotracer F-PSMA-1007, which is physiologically expressed by salivary gland tissue. The F-PSMA-PET/MRI provided evidence of a cystically transformed, diminishing seroma in the left retro-/submandibular region. No F-PSMA expressing glandular tissue could be detected in the area of resection, excluding a relapse of a plunging ranula. As a consequence, we opted for a conservative treatment without further surgical intervention. We conclude that a simultaneous F-PSMA-PET/MRI is a comprehensive imaging modality, which can help to rule out persistent salivary tissue and recurring plunging ranula. It is a useful tool to facilitate the decision making of surgical interventions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394896PMC
http://dx.doi.org/10.3390/diagnostics11081462DOI Listing

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