Control of Gene Expression Lab., Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, 2780-157 Oeiras, Portugal.
Published: August 2021
AI Article Synopsis
Article Abstract
The large production of non-degradable petrol-based plastics has become a major global issue due to its environmental pollution. Biopolymers produced by microorganisms such as polyhydroxyalkanoates (PHAs) are gaining potential as a sustainable alternative, but the high cost associated with their industrial production has been a limiting factor. Post-transcriptional regulation is a key step to control gene expression in changing environments and has been reported to play a major role in numerous cellular processes. However, limited reports are available concerning the regulation of PHA accumulation in bacteria, and many essential regulatory factors still need to be identified. Here, we review studies where the synthesis of PHA has been reported to be regulated at the post-transcriptional level, and we analyze the RNA-mediated networks involved. Finally, we discuss the forthcoming research on riboregulation, synthetic, and metabolic engineering which could lead to improved strategies for PHAs synthesis in industrial production, thereby reducing the costs currently associated with this procedure.
Developing highly efficient non-iridium-based active sites for acidic water splitting is still a huge challenge. Herein, unique Ru-B-Cr moieties have been constructed in RuO nanofibers (NFs) to activate Ru sites for water electrolysis, which overcomes the bottleneck of RuO-based catalysts usually possessing low activity for the hydrogen evolution reaction (HER) and poor stability for the oxygen evolution reaction (OER). The fabricated Cr, B-doped RuO NFs exhibit low overpotentials of 205 and 379 mV for acidic HER and OER at 1 A cm with outstanding stability lasting 1000 and 188 h, respectively.
Copper-based sulfides are attractive candidates for NIR I and II responsive photothermal therapy but often suffer from high hydrophobicity, suboptimal photothermal conversion, and poor biostability and biocompatibility. In the present work, a rapid, one-pot synthesis method was developed to obtain Au-doped CuS (ACSH NDs) dual plasmonic nanodots. ACSH NDs exhibit excellent peroxidase-like catalytic activity for pH-responsive OH radical generation along with efficient glutathione depletion under tumor microenvironment mimicking conditions.
This study assessed the supplemental effect of flushing Menz breeding rams with local agro-industrial by-products on their reproductive performance and semen quality. In a completely randomized design, rams ( 49) with an initial weight of 25.69+2.
Objectives: Assessing children's food and nutrition security in Indonesia, especially among children from parents who experienced child marriage, is crucial for policymakers. This study investigates the role of parental child marriage in children's food security and nutritional status.
Methods: We analyze data from Indonesia Family Life Survey (IFLS) wave 4 (2007) and 5 (2014), involving 1,612 households.
