The objectives of this study were (1) to examine different shapes of lactation curves for milk, fat, protein and lactose yields and urea content in milk fitted by the Wilmink function using the test-day (TD) records and (2) to find the function that best describes test-day records beyond 305 days in milk (DIM) for Polish Holstein-Friesian cows. The data were 6,955,768 TD records from the 702,830 first six lactations of 284,193 Polish Holstein-Friesian cows. Cows calved in 19,102 herds between 2001 and 2018. The following functions were fitted to TD data from each lactation: (1) Wilmink model fitted to the whole lactation, (2) Wilmink model fitted to TD records from 5 to 305 DIM and linear function fitted to TD records from 306 to 400 DIM, (3) Wilmink model fitted to TD records from 5 to 305 DIM and squared function fitted to TD records from 306 to 400 DIM. The present study showed that urea content in milk was modelled slightly worse than other milk traits. The results suggested that the course of lactation could be successfully modelled by a nonlinear model, for example, the Wilmink function, for up to 305 DIM, and by the linear or squared function afterwards.
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http://dx.doi.org/10.3390/ani11082176 | DOI Listing |
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Department of Hematology, Jinhua People's Hospital, No.267, Danxi East Road, Jinhua, 321000, Zhejiang, P.R. China.
Objective: Depression is a common comorbidity in cardiovascular disease (CVD), and both conditions are associated with chronic inflammation. The systemic immune-inflammation index (SII) has emerged as a promising marker of systemic inflammation, but its role in association with depressive symptoms, particularly in the context of CVD, remains unclear. This study aims to investigate the association of SII with depressive symptoms in individuals with and without CVD using cross-sectional data from NHANES (2005-2016).
View Article and Find Full Text PDFNeurochem Res
January 2025
Huazhong University of Science and Technology, Tongji Medical College, Wuhan, Hubei, 430000, China.
Epilepsy (EP) is a neurological disorder characterized by abnormal, sudden neuronal discharges. Seizures increase extracellular glutamate levels, causing excitotoxic damage. Glutamate transporter type 1 (GLT-1) and its human homologue excitatory amino acid transporter-2 (EAAT2) clear 95% of extracellular glutamate.
View Article and Find Full Text PDFEpilepsia Open
January 2025
Division of Pediatric Critical Care Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Objectives: Pediatric status epilepticus (SE) carries a high risk of morbidity and mortality and can result in neurologic injury. Establishing seizure activity on conventional EEG (cEEG) is essential but can delay treatment of seizures due to technician limitations. Rapid response EEG (rrEEG) device Ceribell and its Brain Stethoscope function can be used and interpreted rapidly by bedside providers with minimal training.
View Article and Find Full Text PDFJ Dent Res
January 2025
Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Missing teeth have been linked to incident cardiovascular disease, diabetes, and all-cause mortality. Our previous study revealed that signs of oral infections and inflammatory conditions (i.e.
View Article and Find Full Text PDFJ Neurodev Disord
January 2025
Graduate Neuroscience Program, University of California, Riverside, CA, USA.
Background: Fragile X syndrome (FXS) is a leading known genetic cause of intellectual disability and autism spectrum disorders (ASD)-associated behaviors. A consistent and debilitating phenotype of FXS is auditory hypersensitivity that may lead to delayed language and high anxiety. Consistent with findings in FXS human studies, the mouse model of FXS, the Fmr1 knock out (KO) mouse, shows auditory hypersensitivity and temporal processing deficits.
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