Restorative surgical repair using different surgical modalities is required on the excision of skin lesions or when treating traumatic lacerations; each modality has advantages and drawbacks. In this article, we evaluate the efficacy of using a bilateral interdigitated Pacman flap to reconstruct circular and oval cutaneous defects on different parts of the body. Fourteen patients with soft tissue defects on different parts of the body underwent reconstruction using a bilateral interdigitated Pacman flap. The design of this flap is similar to that of a conventional bilateral V-Y advancement flap; however, the limbs of the V are drawn as slightly curved convex lines. All patients were followed-up for more than 6 months. All soft tissue defects were reconstructed completely using this technique, and no significant complications were noticed except in one patient who developed partial flap necrosis. However, aesthetic issues remain a limiting factor in using this technique. This flap is a reliable, practical and effective option for closure of circular and oval soft tissue defects, although there are certain limitations when used on the face and in younger patients.
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http://dx.doi.org/10.1308/rcsann.2021.0006 | DOI Listing |
bioRxiv
December 2024
Division of Pediatric Neurology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States.
The striatum is divided into two interdigitated tissue compartments, the striosome and matrix. These compartments exhibit distinct anatomical, neurochemical, and pharmacological characteristics and have separable roles in motor and mood functions. Little is known about the functions of these compartments in humans.
View Article and Find Full Text PDFSci Rep
November 2024
Henan Provincial People's Hospital, Henan Eye Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan, China.
To investigate the characteristics of acute visual dysfunction and fundus lesions in patients with COVID-19 pneumonia. A retrospective case series study was conducted. Data from 48 patients (96 eyes) with COVID-19 infection who presented to our ophthalmology department with acute onset visual disturbance between December 5, 2022, and February 28, 2023 were collected.
View Article and Find Full Text PDFRetin Cases Brief Rep
November 2024
Associated Retinal Consultants. Royal Oak, Michigan, USA.
Beyoglu Eye J
September 2024
Department of Ophthalmology, Koc University, Faculty of Medicine, Istanbul, Türkiye.
Am J Ophthalmol Case Rep
June 2024
The Tony and Leona Campane Center for Excellence in Image-Guided Surgery and Advanced Imaging Research, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Purpose: This report aims to highlight the wide spectrum of ophthalmic adverse events associated with erdafitinib, a fibroblast growth factor inhibitor that blocks activation of the mitogen-activated protein kinase kinase (MAPK/MEK) cascade. The purpose of this report is to describe a case of erdafitinib-associated bilateral outer retinal alterations in the MEK-associated retinopathy spectrum and rapid onset bilateral total cataracts following a 20-month course of erdafitinib therapy.
Observations: A 69 year old male with metastatic bladder cancer presented 47 days following treatment initiation with daily erdafitinib (8-mg) with mild new subretinal fluid and minimal associated subretinal debris in the left eye and accentuation/thickening of the interdigitation zone in the right eye.
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