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Nasopharyngeal carriage of Staphylococcus aureus in a rural population, Sierra Leone.
Int J Med Microbiol
December 2024
Institute of Medical Microbiology, University Hospital Münster, Münster, Germany; Masanga Medical Research Unit, Masanga Hospital, Masanga, Sierra Leone.
Background: Nasopharyngeal colonization with Staphylococcus aureus is a risk factor for subsequent infection. Isolates from colonization can therefore provide important information on virulence factors and antimicrobial resistance when data from clinical isolates are lacking. The aim of this study was to assess colonization rates, resistance patterns and selected virulence factors of S.
View Article and Find Full Text PDFNasopharyngeal carriage of Streptococcus pneumoniae among Brazilian children: Interplay with viral co-infection.
PLoS One
January 2025
Federal University of Health Sciences of Porto Alegre, Porto Alegre, RS, Brazil.
Nasopharyngeal transmission of Streptococcus pneumoniae is a prerequisite for the development of pneumococcal diseases. Previous studies have reported a relationship between respiratory viruses and S. pneumoniae infections.
View Article and Find Full Text PDFPrevalence of nasopharyngeal Streptococcus Pneumoniae carriage in infants: A systematic review and meta-analysis of cohort studies and randomized controlled trials.
PLoS One
December 2024
School of General Medicine-2, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
Article Synopsis
- The study investigates the prevalence of nasopharyngeal Streptococcus pneumoniae carriage (NSPC) in infants under two years, focusing on differences by vaccine types and country income levels.
- A systematic review of 49 articles revealed a highest NSPC prevalence in infants aged 4 to 6 months and 7 to 9 months, particularly elevated in low-income countries.
- The findings stress the importance of monitoring NSPC trends, especially non-vaccine serotypes, to inform vaccination strategies and reduce pneumococcal disease burden in infants.
Impact of COVID-19 on Pneumococcal Acute Otitis Media, Antibiotic Resistance, and Vaccination in Children.
Infect Drug Resist
December 2024
Dunarea de Jos" University of Galati, Faculty of Medicine and Pharmacy, Galati, Romania.
Streptococcus pneumoniae is the main pathogen that plays a dual role, on the one hand as an asymptomatic carrier in the nasopharyngeal mucosa and on the other hand directly responsible for triggering invasive pneumococcal infections with various important localizations, especially in the pediatric population. Thus, invasive pneumococcal infections represent one of the main causes of mortality and morbidity in children under 5 years of age. Immunization is a key preventive measure against these infections.
View Article and Find Full Text PDFPneumococcal carriage in a large Sicilian sample population: impact on the current epidemiological scenario and implications for future vaccination strategies.
Front Cell Infect Microbiol
December 2024
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "P. Giaccone", University of Palermo, Palermo, Italy.
Introduction: is a prevalent and virulent global pathogen, with colonization being considered a precondition for pneumococcal disease. Understanding colonization is critical for gaining insights into transmission dynamics and developing effective interventions. This study aimed to determine the prevalence of nasopharyngeal colonization and serotype distribution in the Sicilian population.
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