AI Article Synopsis
- The ability to manipulate and analyze biological components like cells, DNAs, and proteins at high resolution is crucial for understanding biology and enabling early disease diagnosis.
- Progress in plasmonic nanotweezers and nanosensors leverages plasmon-enhanced light-matter interactions for better optical manipulation and analysis at the nanoscale.
- The combination of these technologies with microfluidics in plasmofluidics opens new possibilities for point-of-care (POC) applications, though challenges remain in their development and implementation.
Article Abstract
The capabilities of manipulating and analyzing biological cells, bacteria, viruses, DNAs, and proteins at high resolution are significant in understanding biology and enabling early disease diagnosis. We discuss progress in developments and applications of plasmonic nanotweezers and nanosensors where the plasmon-enhanced light-matter interactions at the nanoscale improve the optical manipulation and analysis of biological objects. Selected examples are presented to illustrate their design and working principles. In the context of plasmofluidics, which merges plasmonics and fluidics, the integration of plasmonic nanotweezers and nanosensors with microfluidic systems for point-of-care (POC) applications is envisioned. We provide our perspectives on the challenges and opportunities in further developing and applying the plasmofluidic POC devices.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382230 | PMC |
| http://dx.doi.org/10.1002/adom.202100050 | DOI Listing |
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