Background: Intramedullary nailing in tibial osteotomy (TO) can be combined with minimally invasive prophylactic fasciotomy (PF) of the anterior compartment of the lower leg to prevent postoperative acute compartment syndrome (CS). So far no studies are available on the effects of TO or PF on specific functions of the extensor muscles.
Objective: To investigate the medium-term outcome after PF in TO in patients without preoperative functional impairment.
Material And Methods: In 41 cases (28 women, 13 men) the patients were questioned with respect to clinical function on average 6.1 years after elective TO and PF fixed with intramedullary nails. Of the cases 23 were examined measuring isometric strength and range of motion (ROM) of dorsiflexion (DF) of the foot. Strength was compared to the 10% standard percentile to test for clinical relevance and to the contralateral side if applicable.
Results: In an average of 86% of the cases no or minor functional impairment of the extensors was reported. The DF of the foot was rated as the leading impairment. Mean strength did not differ significantly from the gender-specific 10% standard percentiles but was significantly lower on the operated side with 16.0 ± 6.5 kgf compared to the healthy side with 17.5 ± 6.3 kgf (p < 0.01). Subjective impairments of DF of the foot correlated clearly negatively with ROM (r = -0.46, p < 0.05) but not with strength.
Conclusion: The results indicate a low occurrence of subjectively relevant functional impairment of the extensor muscles. The decrease of strength was not found to be clinically relevant. Subjective impairments appeared to be caused by a decrease of ROM, not strength.
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http://dx.doi.org/10.1007/s00113-021-01070-y | DOI Listing |
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Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK.
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In chronic lymphocytic leukemia, the reliability of next-generation sequencing (NGS) to detect variants ≤10% allelic frequency (low-VAF) is debated. We tested the ability to detect 23 such variants in 41 different laboratories using their NGS method of choice. The sensitivity was 85.
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In this study, the complete mitochondrial genome of was sequenced by Illumina high-throughput sequencing and its characteristics were analyzed. The mitogenome of is 16,635 bp long, and it encodes the standard set of 13 PCGs, 22 tRNA genes, and two rRNA genes. The mitogenome has a GC content of 29.
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Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, United States.
There are a variety of surgical conditions impacting the canine vagina and vestibule that require access through a caudal approach. A standard vertical episiotomy involves making an incision beginning ventral to the anus and extending ventrally through the dorsal commissure of the vulva and into the lumen of the vestibule and distal vagina. The objective of this study was to determine if complex vaginal procedures could be performed via a transverse perineal approach, thus eliminating the need to incise and reconstruct the vulva as performed in a standard episiotomy, and to evaluate the feasibility of vaginal resection with vulvar-sparing vestibular urethrostomy using this transverse approach.
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