AI Article Synopsis
- Hidradenitis suppurativa (HS) is a chronic skin condition often diagnosed late, leading to severe cases; this study aimed to evaluate the demographics and treatment outcomes of HS patients at a specific outpatient facility.
- The study examined 22 patients, mostly at advanced disease stages, with common treatment options being a combination of antibiotics and sometimes surgery; the best results were seen with both medical and surgical interventions.
- Limitations included the study's retrospective design and being conducted at a single center; findings suggest a multidisciplinary approach improves patient outcomes, highlighting the need for further research.
Article Abstract
Background: Hidradenitis suppurativa (HS) is a chronic debilitating disease with a relapsing and remitting course. Due to delay in diagnosis, patients are often referred when the disease is very severe. Management strategies vary across multiple guidelines.
Aims: The aim of this study was to analyze the demographic and clinical characteristics of patients with HS among our outpatient attendees and to study the outcomes of various treatments offered.
Methodology: This was a retrospective cohort study analyzing case files and photographic records of all patients diagnosed with HS, presenting to our tertiary care institute over 18 months.
Results: A total of 22 patients (10 males and 12 females) of HS were studied with majority having Hurley stage 2 and 3 diseases. The most common site affected was axilla. Overweight and obese patients were 45.4% and 18.1%, respectively. Rifampicin-clindamycin combination or doxycycline was the first line therapy offered. Adalimumab was given in only two patients but could not be continued for long term due to financial issues. Surgery was performed in six patients. Procedures included wide local excision and deroofing which is left to heal by secondary intention. Least number of remissions and most satisfactory improvement was seen with a combination of antibiotics and surgery compared to medical treatment alone.
Limitations: Retrospective nature and a single center study were the major drawbacks.
Conclusion: Patients undergoing procedural intervention in addition to pharmacotherapy have best overall outcomes and involvement of a multidisciplinary team plays a key role, however a larger follow-up study is required.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354385 | PMC |
| http://dx.doi.org/10.4103/idoj.IDOJ_743_20 | DOI Listing |
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