An improved method for detecting abnormal oceanic temperature and salinity (T/S) profiles is developed. This procedure extends previous method developed by Udaya Bhaskar et al. [2017]. This method utilizes World Ocean Atlas 2013 gridded climatology which is on 0.25° x 0.25° resolution to build α convex hulls. These α shapes are then used to categorize good and bad T/S data profiles. This extended method classify the entire profiles instead of data for standard depths to avoid any errors introduced by interpolation to standard depths. Like in previous method, an 'n' sided polygon (convex hull) encompassing the T/S profile data is constructed using Jarvis March algorithm and Points In Polygon (PIP) principle is employed to judge the profile as good or bad. Extensive sensitivity experiments were done for arriving at the optimal α value such that false positives and true negatives are minimized. All types of issues associated with the oceanographic data are identified and quality flag assigned. Examples of this improved method as applied to few Argo floats are presented.•The T/S profiles corresponding to region of interest are used to build α convex hulls.•This extended method can be effectively used for quality control of entire profile and clearly demarcate the profile as good/bad.•This method has the advantage of treating bulk of oceanographic profiles data in a single go which filters out erroneous profile data from the good.
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http://dx.doi.org/10.1016/j.mex.2021.101337 | DOI Listing |
Allergy Asthma Proc
January 2025
From the Section of Allergy, Asthma and Immunology, Medicine and Pediatrics, Pennsylvania State University School of Medicine, Hershey, Pennsylvania and.
Patients with mast cell activation syndrome (MCAS) can be refractory to standard antimediator therapy. Alternative treatment options to reduce disease burden and improve quality of life are needed. To compile the evidence that supports the use of omalizumab for patients with refractory MCAS.
View Article and Find Full Text PDFAllergy Asthma Proc
January 2025
2nd Respiratory Department, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Remission of asthma can occur as part of the natural history of the disease; however, the use of biologics can result in disease remission in some patients. In this post hoc analysis of the RELIght study, we aimed to evaluate clinical remission in real life among patients treated with mepolizumab, to detect possible differences between "remitters" and "nonremitters," and to evaluate possible predictors of remission. Clinical remission was defined as the absence of asthma exacerbations, discontinuation of oral corticosteroids (OCS), achievement of asthma control (Asthma Control Test [ACT] ≥ 20), and stable or improved lung function.
View Article and Find Full Text PDFImplement Sci Commun
December 2024
Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02115, USA.
Background: Doulas, non-clinical professionals who provide support throughout the perinatal period, can positively impact patient experiences and clinical outcomes during birth. Doulas often support hospital-based births without being employed by the hospital system, resulting in varied relationships with hospitals and clinicians. Systems-level changes are needed to maximize collaboration between hospitals and doulas to ensure facilitation of, and not barriers to, doula support.
View Article and Find Full Text PDFBiol Direct
December 2024
Key Laboratory of Animal Genetics Breeding and Reproduction, Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Background: Integrating multi-layered information can enhance the accuracy of genomic prediction for complex traits. However, the improvement and application of effective strategies for genomic prediction (GP) using multi-omics data remains challenging.
Methods: We generated 11 feature sets for sequencing variants from genomics, transcriptomics, metabolomics, and epigenetics data in beef cattle, then we assessed the contribution of functional variants using genomic restricted maximum likelihood (GREML).
J Orthop Surg Res
December 2024
School of Rehabilitation Medicine, Henan University of Chinese Medicine, Zhengzhou, China.
Objective: Ankle osteoarthritis is a debilitating condition that significantly impairs patients' quality of life. Platelet-rich plasma has emerged as a novel cellular therapy in clinical practice. This study evaluates the clinical efficacy of platelet-rich plasma (PRP) after intervention in ankle disorders, so as to provide strong evidence in support of clinical treatment.
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