Stem cell niche signaling goes both ways.

Dev Cell

Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Howard Hughes Medical Institute, Cambridge, MA, USA; Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address:

Published: August 2021

Stem cell niches are well-characterized factories of signaling information, but niche cells themselves also rely on their neighbors for fate maintenance. In this issue of Developmental Cell, Herrera et al. reveal bi-directional communication between Drosophila testis niche "hub" cells and somatic cyst stem cells.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290821PMC
http://dx.doi.org/10.1016/j.devcel.2021.08.003DOI Listing

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