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Resolution of long standing hypergammaglobulinemic purpura of Waldenström after initiating treatment for cystic fibrosis with Elexacaftor-Tezacaftor-Ivacaftor.
JAAD Case Rep
February 2024
Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Hypergammaglobulinemic purpura misdiagnosed as IgA vasculitis in a girl with primary Sjögren syndrome.
Int J Rheum Dis
October 2023
Division of Pediatrics, National Hospital Organization Fukuokahigashi Medical Center, Koga, Japan.
Pathophysiology and clinical manifestations of immune complex vasculitides.
Front Med (Lausanne)
March 2023
Department of Dermatology and Venereology, University Hospital Halle, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Immune complex (IC) vasculitides present inflammations of vessel walls associated with perivascular deposition of immunoglobulins (Igs), mostly ICs. They encompass systemic and skin-limited variants of IgA vasculitis (IgAV), cryoglobulinemic vasculitis (CV), rheumatoid, lupus, and hypocomplementemic vasculitides, serum sickness cutaneous IgM/IgG (non-IgA) vasculitis, and recurrent macular (hypergammaglobulinemic or exertion-induced) vasculitis. Serum sickness and CV fulfill the criteria of a type III hypersensitivity immune reaction as large lattices of the IC precipitate at vessel walls and activate polymorphonuclear neutrophils (PMNs).
View Article and Find Full Text PDFHypergammaglobulinemic purpura of Waldenström-Unusual and impressive case in a patient with myeloma: A case report.
SAGE Open Med Case Rep
March 2022
Division of Dermatology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Background: Hypergammaglobulinemic purpura of Waldenström is an uncommon disease, which presents mostly in women on the lower extremities. It is sometimes associated with underlying immune dysregulation. Sjögren syndrome is the most common association; however, rare occurrences of the self-resolving syndrome with lymphoma or myeloma have been reported.
View Article and Find Full Text PDFHypergammaglobulinemic purpura: Does hypergammaglobulinemia cause purpura?
J Dermatol
November 2021
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan.
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