The main stages and achievements in the investigation of the fate of mRNA in eukaryotic cells, which began half a century ago with the discovery of informosomes by A.S. Spirin, there are discussed. The results of even the most recent studies confirm Spirin's hypotheses about the structure and function of the informosomes, now called mRNPs. In the bibliography, we present only small part of the published articles in this field. The full list is too large.
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