The paper presents the monitoring results of the temporal variability of daily Be activity concentration in the atmospheric surface layer at Sevastopol in 2011-2020. The Be activity concentration in individual samples of atmospheric aerosols varies from 0.1 to 13.3 mBq m and averages 4.0 ± 2.0 Bq m. Higher Be activity concentrations have been observed during the period from May to August while lower concentrations have been measured from December to January. Quantitative estimates of the influence of precipitation (amount, duration, intensity) on the temporal variability of Be activity concentration have been obtained. It has been found that daily Be activity concentration decrease by 2-82% on the first day with precipitation. It has been shown that an increase in precipitation duration and a decrease in its intensity lead to a more significant decrease in the daily Be activity concentration. The estimates of the scavenging coefficient have been obtained; the average value is 0.6 ± 1.0 h. An increase in the precipitation intensity or amount is accompanied by a decrease in the Be scavenging coefficient. Mean 0.5-folding and residence times of Be activity concentration in the atmosphere during a moderate rain event are 2.9 ± 2.2 and 15.4 ± 13.6 h, respectively. The recovery of Be activity concentration in the atmosphere after precipitation has been investigated. It has been found that this process takes 1-2 days. The mean value of the reload coefficient is 0.94 ± 0.34 d. The relationship between the value of the reload coefficient and local meteorological parameters (air temperature, relative humidity, atmospheric pressure, wind speed, surface net solar radiation flux) has been investigated. No statistically significant correlations at a 95% confidence level between the reload coefficient and the considered meteorological parameters have been revealed. Parameterization describing a decrease in the daily Be activity concentration in the atmosphere due to precipitation and its recovery during the precipitation-free period has been introduced.
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http://dx.doi.org/10.1016/j.jenvrad.2021.106722 | DOI Listing |
BMC Pharmacol Toxicol
January 2025
Department of Anatomy, College of Health Sciences, University of Ilorin, Ilorin, 240003, Nigeria.
Background: Glia mediated neuroinflammation and degeneration of inhibitory GABAergic interneurons are some of the hall marks of pyrethroid neurotoxicity. Here we investigated the sex specific responses of inflammatory cytokines, microglia, astrocyte and parvalbumin positive inhibitory GABAergic interneurons to λ-cyhalothrin (LCT) exposures in rats.
Methods: Equal numbers of male and female rats were given oral corn oil, 2 mg/kg.
BMC Microbiol
January 2025
Center for Public Health Research, Medical School of Nanjing University, Nanjing, China.
Background: Enterovirus 71 (EV71) is one of the major causative agents of hand, foot, and mouth disease (HFMD), and can cause severe cerebral complications and even fatality in children younger than 5 years old. However, there is no specific medication for EV71 infection in clinical practice. Our previous studies had identified the 6-thioguanine (6-TG), an FDA-approved anticancer drug, as a potential antiviral agent, but its anti-EV71 activity is largely unknown, therefore, we aim to explore the antiviral effect of 6-TG on EV71.
View Article and Find Full Text PDFJ Orthop Traumatol
January 2025
Italian National Registry of Implantable Prostheses (RIPI), Italian National Institute of Health, Viale Regina Elena 299, 00161, Rome, Italy.
Background: Treatment of ankle osteoarthritis by total ankle replacement (TAR) is increasing worldwide. The aim of the study was to present the overall temporal trends of TAR throughout 22 years (2001-2022) in Italy, analyzing the distributions of hospitals by volume of activity and patients by age and sex, drawing on the National Hospital Discharge Record database. Furthermore, as a secondary aim, we compared these trends with those of ankle fusions.
View Article and Find Full Text PDFSci Rep
January 2025
College of Hydraulic and Civil Engineering, Xinjiang Agricultural University, Urumqi, 830052, Xinjiang, People's Republic of China.
Aiming at the problem that it is difficult to realize low-cost, high-performance and large-scale utilization of cementitious materials prepared from bulk solid wastes, this paper constructs a set of composite cementitious system based on alkaline activation of slag and fly ash (FA) by calcium carbide slag (CCS) and synergistic activation of sodium sulfate (NaSO) as a chemical dopant. The influence of factors such as solid waste type, mixing ratio, and NaSO content on the mechanical properties of composite cementitious systems was investigated by assessing compressive strength and analyzing microstructure using XRD, SEM-EDS, and FTIR. The test results indicate that CCS and NaSO exert significant influences on the strength of the composite cementitious system.
View Article and Find Full Text PDFNat Biomed Eng
January 2025
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.
The utility of urinary tests for the monitoring of the treatment efficacy and adverse events of anticancer therapies is constrained by the low concentration of relevant urinary biomarkers. Here we report, using mice with lung cancer and treated with chemotherapy, of a urinary fluorescence test for the concurrent monitoring of the levels of a tumour biomarker (cathepsin B) and of a biomarker of chemotherapy-induced kidney injury (N-acetyl-β-D-glucosaminidase). The test involves two intratracheally administered urinary reporters leveraging caged bioorthogonal click handles for the biomarker-dependent activation of 'clickability' and renal clearance, and the bioorthogonal click reaction of each renally cleared reporter with paired fluorescence indicators in the collected urine.
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