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Biologia futura: confessions in genes.
Biol Futur
December 2020
Institute of Forensic Genetics, Hungarian Institute for Forensic Sciences, PO: 314/4, Budapest, 1903, Hungary.
Y-DNA and mtDNA have been a widely used tool not only in forensic genetic applications but in human evolutionary and population genetic studies. Its paternal or maternal inheritance and lack of recombination have offered the opportunity to explore genealogical relationships among individuals and to study the frequency differences of paternal and maternal clades among human populations at continental and regional levels. It is unbelievable, but true, that the disadvantages of paternal and maternal lineages in forensic genetic studies, i.
View Article and Find Full Text PDFAncient Y-DNA with reconstructed phylogeny provides insights into the demographic history of paternal haplogroup N1a2-F1360.
J Genet Genomics
December 2021
School of Life Sciences, Jilin University, Changchun 130012, China; Research Center for Chinese Frontier Archaeology of Jilin University, Jilin University, Changchun 130012, China. Electronic address:
Y-DNA genetic evidence reveals several different ancient origins in the Brahmin population.
Mol Genet Genomics
January 2021
DGM Associates, Pacific Palisades, CA, USA.
The ancient geographical origins of Brahmins-a prominent ethnic group in the Indian subcontinent-have remained controversial for a long time. This study employed the AMOVA (analysis of molecular variance) test to evaluate genetic affinities of this group with thirty populations of Central Asia and Europe. A domestic comparison was performed with fifty non-Brahmin groups in India.
View Article and Find Full Text PDFGenetic history of Chad.
Am J Phys Anthropol
December 2018
Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, Maryland.
Objectives: The Sahel is a semi-arid zone stretching from the Atlantic Ocean in the west to the Red Sea in the east and from the Sahara in the north to the Sudanian Savanna in the south. Here, we investigated the genetic history of the spread of Northern African ancestry common among Berbers, the Y DNA haplogroup R1b-V88, and Chadic languages throughout the Sahel, with a focus on Chad.
Materials And Methods: We integrated and analyzed genotype data from 751 individuals from Chad, Burkina Faso, Mali, South Sudan, and Sudan in the context of a global reference panel of 5,966 individuals.
In-solution Y-chromosome capture-enrichment on ancient DNA libraries.
BMC Genomics
August 2018
International Laboratory for Human Genome Research, National Autonomous University of Mexico, Mexico, Mexico.
Background: As most ancient biological samples have low levels of endogenous DNA, it is advantageous to enrich for specific genomic regions prior to sequencing. One approach-in-solution capture-enrichment-retrieves sequences of interest and reduces the fraction of microbial DNA. In this work, we implement a capture-enrichment approach targeting informative regions of the Y chromosome in six human archaeological remains excavated in the Caribbean and dated between 200 and 3000 years BP.
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