It has been reported that DIC can react with OxymaPure to render an oxadiazole compound with the concomitant formation of HCN. Here we demonstrate that this reaction is not a feature of all carbodiimides but rather depends on the alkyl structure that flanks the two N atoms of the carbodiimide. Furthermore, we have identified two carbodiimides, TBEC and EDC·HCl, whose reaction with OxymaPure is exempt from HCN formation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487715 | PMC |
| http://dx.doi.org/10.1021/acs.orglett.1c02466 | DOI Listing |
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