AI Article Synopsis

  • The study analyzed the secondary attack rate (SAR) of COVID-19 among 2,382 close contacts of 476 symptomatic individuals in Yichang, China, from January 23 to February 25, 2020.
  • The overall SAR was 6.5%, with higher rates observed among those living with an infected person (10.8%) and spouses of infected individuals (15.9%).
  • Factors like being over 60 years old and living with the infected person significantly increased the SAR, indicating a high transmissibility of the virus.

Article Abstract

We estimated the symptomatic, PCR-confirmed secondary attack rate (SAR) for 2,382 close contacts of 476 symptomatic persons with coronavirus disease in Yichang, Hubei Province, China, identified during January 23-February 25, 2020. The SAR among all close contacts was 6.5%; among close contacts who lived with an index case-patient, the SAR was 10.8%; among close-contact spouses of index case-patients, the SAR was 15.9%. The SAR varied by close contact age, from 3.0% for those <18 years of age to 12.5% for those >60 years of age. Multilevel logistic regression showed that factors significantly associated with increased SAR were living together, being a spouse, and being >60 years of age. Multilevel regression did not support SAR differing significantly by whether the most recent contact occurred before or after the index case-patient's onset of illness (p = 0.66). The relatively high SAR for coronavirus disease suggests relatively high virus transmissibility.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386800PMC
http://dx.doi.org/10.3201/eid2709.202035DOI Listing

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