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| http://dx.doi.org/10.1016/j.gendis.2021.08.001 | DOI Listing |
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Transcriptional coupling of telomeric retrotransposons with the cell cycle.
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Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, Louisiana Cancer Research Center, 1700 Tulane Avenue, New Orleans, LA 70112, USA.
Unlike most species that use telomerase for telomere maintenance, many dipterans, including , rely on three telomere-specific retrotransposons (TRs)-, , and -to form tandem repeats at chromosome ends. Although TR transcription is crucial in their life cycle, its regulation remains poorly understood. This study identifies the Mediator complex, E2F1-Dp, and Scalloped/dTEAD as key regulators of TR transcription.
View Article and Find Full Text PDFBeyond the Nest: The Role of Financial Independence in Young Adult Health.
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Department of Psychology, Georgia State University, 140 Decatur Street, Suite 1150 Urban Life Building, Atlanta, GA, 30303, USA.
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Annexin A1 expression in Lupus Nephritis.
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View Article and Find Full Text PDFMoral disengagement as mediator and guilt as moderator between cyber moral literacy and cyberbullying among late adolescents.
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Chinese Academy of Education Big Data, Qufu Normal University, Qufu, Shandong, China.
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View Article and Find Full Text PDFDetection of exon2-MED12 mutations in uterine leiomyomas from Syrian patients.
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Department of Pathology, Faculty of Medicine, Damascus University, Damascus, Syria.
Uterine leiomyomas (uLMs) are the most prevalent benign tumors of the female reproductive system. MED12 is one of the mediator complex subunits that has been implicated in uLMs pathogenesis. Somatic mutations in exon2-MED12 have been found in ~ 70% of uLMs.
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