[Prevention of infections by influenza virus and respiratory syncytial virus after removal of the lockdown measures].

Monatsschr Kinderheilkd

Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital, Ludwig-Maximilians-Universität, Lindwurmstr. 4, 80337 München, Deutschland.

Published: August 2021

There have recently been reports of unusual outbreaks of respiratory infections in children due to influenza virus and respiratory syncytial virus (RSV) during the summer in the southern hemisphere. This phenomenon is attributed to the termination of the drastic hygiene measures to contain the pandemic triggered by the coronavirus disease 2019 (COVID-19). The affected children were much older than anticipated. Coincident with the end of the present lockdown in summer, a similar situation could develop in Germany. Physicians and hospitals should be alerted to such a possibility. Interseasonal vaccines are not available for influenza but passive immunization against RSV could help to protect infants for whom appropriate indications exist according to the guidelines.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369864PMC
http://dx.doi.org/10.1007/s00112-021-01278-7DOI Listing

Publication Analysis

Top Keywords

influenza virus
8
virus respiratory
8
respiratory syncytial
8
syncytial virus
8
[prevention infections
4
infections influenza
4
virus
4
virus removal
4
removal lockdown
4
lockdown measures]
4

Similar Publications

Neutrophils play key protective roles in influenza infections, yet excessive neutrophilic inflammation is a hallmark of acute lung injury during severe infections. Phenotypic heterogeneity is increasingly recognized in neutrophil populations; however, how functional variation in neutrophils between individuals determine the diverse outcomes of influenza remains unclear. To examine immunologic responses that may drive varying outcomes in influenza, we infected C57BL/6 (B6) and A/J mice with mouse-adapted influenza A virus A/PR/8/34 H1N1.

View Article and Find Full Text PDF

Mucin Colocalizes with Influenza Virus and Preserves Infectivity in Deposited Model Respiratory Droplets.

Environ Sci Technol

January 2025

Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, Virginia 24061, United States.

The stability of influenza virus in respiratory particles varies with relative humidity (RH) and protein content. This study investigated the decay, or loss of infectivity, of influenza A virus (IAV) in 1-μL respiratory droplets deposited on a surface with varying concentrations of mucin, one of the most abundant proteins in respiratory mucus, and examined the localization of virions within droplets. IAV remained stable at 0.

View Article and Find Full Text PDF

Reaction-advection-diffusion model of highly pathogenic avian influenza with behavior of migratory wild birds.

J Math Biol

January 2025

School of Mathematics and Statistics, Northeast Normal University, 5268 Renmin Street, Changchun, 130024, Jilin, People's Republic of China.

Wild birds are one of the main natural reservoirs for avian influenza viruses, and their migratory behavior significantly influences the transmission of avian influenza. To better describe the migratory behavior of wild birds, a system of reaction-advection-diffusion equations is developed to characterize the interactions among wild birds, poultry, and humans. By the next-generation operator, the basic reproduction number of the model is formulated.

View Article and Find Full Text PDF

Objectives: Given the ongoing challenges regarding the specific roles of viral infections in cancer etiology, or as cancer co-morbidities, this study assessed potential associations between anti-viral, T-cell receptor (TCR) complementarity domain region-3 (CDR3s), and clinical outcomes for ovarian cancer.

Methods: TCR CDR3s were isolated from ovarian cancer specimens for a determination of which patients had anti-viral CDR3s and whether those patients had better or worse outcomes.

Results: Analyses revealed that patients with exact matches of anti-Epstein-Barr virus (EBV) CDR3 amino acid sequences exhibited better outcomes for both overall and disease-specific survival.

View Article and Find Full Text PDF

Cigarette smoke components modulate the MR1-MAIT axis.

J Exp Med

February 2025

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Australia.

Tobacco smoking is prevalent across the world and causes numerous diseases. Cigarette smoke (CS) compromises immunity, yet little is known of the components of CS that impact T cell function. MR1 is a ubiquitous molecule that presents bacterial metabolites to MAIT cells, which are highly abundant in the lungs.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!