Chitosan is a biopolymer that is natural, biodegradable, and relatively low price. Chitosan has been attracting interest as a matrix of nanocomposites due to new properties for various applications. This study presents a comprehensive overview of common and recent advances using chitosan as a nanocomposite matrix. The focus is to present alternative processes to produce embedded or coated nanoparticles, and the shaping techniques that have been employed (3D printing, electrospinning), as well as the nanocomposites emerging applications in medicine, tissue engineering, wastewater treatment, corrosion inhibition, among others. There are several reviews about single chitosan material and derivatives for diverse applications. However, there is not a study that focuses on chitosan as a nanocomposite matrix, explaining the possibility of nanomaterial additions, the interaction of the attached species, and the applications possibility following the techniques to combine chitosan with nanostructures. Finally, future directions are presented for expanding the applications of chitosan nanocomposites.
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http://dx.doi.org/10.1016/j.carbpol.2021.118472 | DOI Listing |
PeerJ
January 2025
Department of Biology, School of Sciences and Humanities, Nazarbayev University, Astana, Kazakhstan.
Background: Chitosan nanoparticles (CsNPs) are an effective and inexpensive approach for DNA delivery into live cells. However, most CsNP synthesis protocols are not optimized to allow long-term storage of CsNPs without loss of function. Here, we describe a protocol for CsNP synthesis, lyophilization, and sonication, to store CsNPs and maintain transfection efficiency.
View Article and Find Full Text PDFHospital wastewater (HWW) is a major pollutant that presents significant risks to both environmental and human health. In this study, we developed a novel, inexpensive and highly antibacterial magnetic nanocomposite composed of FeO nanoparticles synthesised from spent pickling liquors, coated with chitosan and then integrated with polyhexamethylene guanidine hydrochloride (FeO@CS@PHMG) using sodium tripolyphosphate (TPP) as a crosslinking agent. The obtained results revealed that the synthesised nanocomposite exhibited high antibacterial activity against and .
View Article and Find Full Text PDFRSC Adv
January 2025
Nanoscience Research Laboratory, Department of Chemistry, Shivaji University Kolhapur 416 004 Maharashtra India
This research investigates the microbial inactivation potential of ternary TiO-CuO-chitosan nanocomposites (TCC NCs) applied as surface coatings on cowhide leather. Initially, bare TiO nanoparticles (NPs) and binary TiO-CuO (TC) NCs, with varying CuO NPs content, were prepared using an sol-gel method. These binary TC NCs were then modified with chitosan at varying weight percentages (2%, 4%, 6%, and 8%).
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Senior Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China.
Repairing large bone defects remains a significant clinical challenge. Stem cell is of great importance in bone regeneration, and periosteum is rich in periosteal stem cell, which has a great influence on repairing bone defects. Bioengineered periosteum with excellent biocompatibility and stem cell homing capabilities to promote bone regeneration is of great clinical significance.
View Article and Find Full Text PDFTher Deliv
January 2025
Faculty of Fundamental Sciences, Van Lang University, Ho Chi Minh City, Vietnam.
Natural hydrogels have garnered increasing attention due to their natural origins and beneficial roles in wound healing. Hydrogel water-retaining capacity and excellent biocompatibility create an ideal moist environment for wound healing, thereby enhancing cell proliferation and tissue regeneration. For this reason, naturally derived hydrogels formulated from biomaterials such as chitosan, alginate, gelatin, and fibroin are highly promising due to their biodegradability and low immunogenic responses.
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