AI Article Synopsis
- - Six new bisabolane-type phenolic sesquiterpenoids were discovered from the marine sponge Plakortis simplex in the South China Sea, named plakordiols A-D (1-4) and two hydroxycurcudiols (5-6).
- - The structures of these compounds were identified using in-depth spectroscopic analysis, with configurations determined through methods like coupling constant analysis and NOESY correlations.
- - The researchers evaluated the cytotoxic and antibacterial properties of these newly isolated compounds.
Article Abstract
Six new bisabolane-type phenolic sesquiterpenoids, including plakordiols A-D (1-4), (7R, 10R)-hydroxycurcudiol (5) and (7R, 10S)-hydroxycurcudiol (6) were isolated from the marine sponge Plakortis simplex collected from the South China Sea. Their structures were determined based on extensive analysis of spectroscopic data. Their configurations were assigned by coupling constant analysis, NOESY correlations, and the modified Mosher's method. Furthermore, their cytotoxic and antibacterial activities were evaluated.
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| http://dx.doi.org/10.1016/S1875-5364(21)60062-6 | DOI Listing |
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