Studies using probability samples have yielded cross-sectional and longitudinal associations between relationship dissolution and psychopathology, including depressive, anxiety, and substance use symptoms and disorders. The present review summarizes theory relevant to the association of relationship dissolution to psychopathology, discusses the time course over which postdissolution psychopathology may be most likely to manifest, and selectively reviews empirical findings regarding main and moderated associations between relationship dissolution and psychopathology. We conclude by acknowledging the need for continued study of the association between relationship dissolution and psychopathology, including research that rules out potential rival explanations (i.e., confounding variables) for this association and examines this association across cultures and types of intimate relationships (e.g., cohabiting relationships).
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http://dx.doi.org/10.1016/j.copsyc.2021.07.016 | DOI Listing |
Pharm Res
January 2025
Solid State Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, 835215, Jharkhand, India.
Improving the bioavailability of poorly water-soluble drugs presents a significant challenge in pharmaceutical development. Amorphous solid dispersions (ASDs) have garnered substantial attention for their capability to augment the solubility and dissolution rate of poorly water-soluble drugs, thereby markedly enhancing their bioavailability. ASDs, characterized by a metastable equilibrium where the active pharmaceutical ingredient (API) is molecularly dispersed, offer enhanced absorption compared to crystalline forms.
View Article and Find Full Text PDFInt J Pharm
January 2025
Faculty of Pharmacy, Almarisah Madani University, Makassar, Indonesia; Department of Pharmacy and Pharmaceutical Technology, Almarisah Madani University, Makassar, Indonesia. Electronic address:
The combination of the active compounds curcumin and piperine (CP) is effective as an antimalarial; however, the solubility and bioavailability of CP are very low. This study aims to formulate CP in nanoparticles (NP), which are then fabricated into dissolving microneedles (DMN). The NPs were prepared with a concentration ratio of CP-Chitosan-So.
View Article and Find Full Text PDFJ Environ Manage
January 2025
BQE Water, Vancouver, BC, Canada.
Biological semi-passive mine water treatment technologies are used in the mining industry as an alternative to or in conjunction with active treatment systems to remediate mine impacted water (MIW) containing nitrate and selenium oxyanions such as selenate and selenite. In semi-passive biological treatment systems, MIW is pumped through a saturated, porous media (either a gravel bed or waste rock) which provides ample surface area for biofilm growth and the creation of anoxic, subaqueous environments. Additional nutrients and carbon sources are pumped into the system to encourage the growth of microbes that biochemically reduce selenate and selenite to insoluble reduced Se species such as selenium nanoparticles (SeNP) by respiring selenate and selenite.
View Article and Find Full Text PDFJ Colloid Interface Sci
January 2025
School of Materials Science and Engineering, State Key Laboratory of Marine Resource Utilization in South China Sea, Hainan University, Haikou, Hainan 570228, China. Electronic address:
Emerging of the lattice oxygen mechanism (LOM) provides a new opportunity for enhancing oxygen evolution reaction (OER) activity. However, its stability suffers from metal cation dissolution and lattice oxygen anionic redox chemistry. In this paper, carbon dots (CDs)-modified nickel-iron MOF (Metal-Organic Framework) nanosheets (NiFe-BDC/CDs) were prepared for efficient OER electrocatalysis.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Department of Biomaterials, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 7008558, Japan. Electronic address:
Bone-eating (also known as osteophagia), found in wild animals, is primarily recognized as a means to supplement phosphorus and calcium intake. Herein, we describe a novel function of bone-eating in detoxifying heavy metal ions through the dissolution and co-precipitation of bone minerals as they travel through the gastrointestinal (GI) tract. In this study, cadmium (Cd), a heavy metal ion, served as a toxic model.
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