This paper discusses two retrodictions of the theory of ratchet universality which explain previous experimental results concerning directed ratchet transport of cold atoms in dissipative optical lattices in one case and of fluxons in uniform annular Josephson junctions in the other, both driven by biharmonic fields. It has to be emphasized that these retrodictions are in sharp contrast with the current standard explanation of such experimental results, and they offer optimal control of the ratchetlike motion of such entities. New experimental proposals with cold atoms and fluxons are discussed, providing additional tests for novel predictions from ratchet universality.
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http://dx.doi.org/10.1103/PhysRevE.104.014120 | DOI Listing |
Traditional magneto-optical traps are often bulky and complex, which limits their application in portable and scalable technologies. In this study, we propose a method for generating cold atoms using a transmission-grating-based magneto-optical trap (TGMOT). This approach addresses the limitations of traditional magneto-optical traps using a transmission-grating design that simplifies the optical configuration, allowing for efficient atom capture with a single incident beam.
View Article and Find Full Text PDFSci Rep
January 2025
Key Laboratory of Optoelectronic Sensing and Intelligent Control, Hubei University of Science and Technology, Xianning, 437100, China.
We present a novel approach to realize three-dimensional (3D) matter wave solitons (MWSs) transformation between different optical potential wells by manipulating their depths and centers. The 3D MWSs are obtained by the square operator method, and transformed to other types (elliptical/ring/necklace) by performing time evolution with the split-step Fourier method. The effectiveness and reliability of our approach is demonstrated by comparing the transformed solitons with those obtained iteratively using the square operator method.
View Article and Find Full Text PDFJ Med Chem
January 2025
Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.
In this study, a novel antibody-drug conjugate (ADC) consisting of Rituximab and Chlorambucil (Rituximab-CMB) was synthesized. The average number of drug molecules attached per Rituximab molecule was determined using MALDI-TOF mass spectrometry, revealing a range of 4-6 drug molecules per antibody. To further improve the therapeutic potential of the ADC, it was radiolabeled with the therapeutic radionuclide Lu via a DOTA chelator, achieving a final radiochemical purity of over 95%.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
December 2024
Anhui University of Chinese Medicine Hefei 230012, China Anhui Province Key Laboratory of Application and Transformation of Traditional Chinese Medicine in Prevention and Treatment of Major Pulmonary Diseases Hefei 230031, China Key Laboratory of Xin'an Medicine, Ministry of Education Hefei 230038, China.
This study aimed to investigate the mechanism by which Shegan Mahuang Decoction(SGMH) and its bitter Chinese herbs(BCHs) regulated the lung-gut axis through the bitter taste receptor 14(TAS2R14)/secretory immunoglobulin A(SIgA)/thymic stromal lymphopoietin(TSLP) to intervene in the epithelial cell barrier of cold asthma rats. Fifty SD rats were randomly divided into the following five groups: normal group, model group, dexamethasone group, SGMH group, and BCHs group. A 10% ovalbumin(OVA) solution was used to sensitize the rats via subcutaneous injection on both sides of the abdomen and groin, combined with 2% OVA atomization and cold(2-4 ℃) stimulation to induce a cold asthma model in rats.
View Article and Find Full Text PDFMolecules
December 2024
School of Electrical Engineering, Shandong University, Jinan 250061, China.
In recent years, plasma medicine has developed rapidly as a new interdisciplinary discipline. However, the key mechanisms of interactions between cold atmospheric plasma (CAP) and biological tissue are still in the exploration stage. In this study, by introducing the reactive molecular dynamics (MD) simulation, the capsid protein (CA) molecule of HIV was selected as the model to investigate the reaction process upon impact by reactive oxygen species (ROS) from CAP and protein molecules at the atomic level.
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