A Prospective Evaluation of Intraoperative Indocyanine Green Fluorescence Angiography for Soft Tissue Sarcomas.

J Am Acad Orthop Surg Glob Res Rev

From the Department of Orthopedic Surgery (Dr. Wilke, Dr. Schultz, Dr. Sherman, Dr. Murray, Dr. Forte), the Division of Plastic Surgery (Dr. Huayllani, Dr. Boczar, Dr. Forte); and the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery (Dr. Huayllani, Dr. Boczar, Dr. Spaulding, Dr. Forte), Mayo Clinic, Jacksonville, Florida.

Published: August 2021

AI Article Synopsis

  • The study focused on using Indocyanine green (ICG) angiography to predict and reduce wound complications after soft-tissue sarcoma surgery.
  • A prospective study from 2017 to 2019 compared wound complication rates in 88 patients who underwent surgery with ICG angiography against historical data from surgeries without it.
  • Results showed that the use of ICG significantly reduced infection rates (11.8% vs. 38%) and wound dehiscence (11.8% vs. 42.3%), suggesting that ICG angiography might be a valuable tool in improving surgical outcomes.

Article Abstract

Introduction: Postoperative wound complications after resection of soft-tissue sarcomas are challenging. Indocyanine green (ICG) angiography has previously been used to predict wound complications, but not for soft-tissue sarcomas. We aimed to evaluate whether this technology could help lower wound complications after soft-tissue sarcoma resections.

Materials And Methods: We conducted a prospective study from 10/2017 to 9/2019 using ICG angiography during sarcoma resection surgery. Rates of wound complications were compared with a historical control consisting of surgeries before utilization of ICG angiography.

Results: A total of 88 patients were included in the study. We found significantly lower rates of infection (11.8% versus 38%; P = 0.03) and wound dehiscence (11.8% versus 42.3%; P = 0.02) in the ICG angiography cohort compared with the historical controls.

Conclusion: ICG angiography use during soft-tissue sarcoma resections is promising technology and warrants further investigation to help reduce postoperative complications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378787PMC
http://dx.doi.org/10.5435/JAAOSGlobal-D-21-00187DOI Listing

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