Contact tracing and quarantine are well established non-pharmaceutical epidemic control tools. The paper aims to clarify the impact of these measures in evolution of epidemic. The proposed deterministic model defines a simple rule on the reproduction number [Formula: see text] in terms of ratio of diagnosed cases and, quarantine and transmission parameters. The model is applied to the early stage of Covid19 crisis in Poland. We investigate 3 scenarios corresponding to different ratios of diagnosed cases. Our results show that, depending on the scenario, contact tracing prevented from 50% to over 90% of cases. The effects of quarantine are limited by fraction of undiagnosed cases. The key conclusion is that under realistic assumptions the epidemic can not be controlled without any social distancing measures.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372969 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0256180 | PLOS |
Virol J
December 2024
Department of Molecular and Translational Medicine, Section of Microbiology, University of Brescia, Piazzale Spedali Civili, 1, Brescia, 25123, Italy.
Background: Since the beginning of the pandemic, contact tracing has been one of the most relevant issues to understand SARS-CoV-2 transmission dynamics and, in this context, the analysis of quasispecies may turn out to be a useful tool for outbreak investigations. Analysis of the intra-host single nucleotide variants (iSNVs) found in the nsp2, ORF3, and ORF7 genes of SARS-CoV-2 was conducted in order to correctly identify virus transmission chain among patients hospitalized in Brescia Civic Hospital.
Methods: During the period between August and October 2023, 13 nasopharyngeal specimens, collected from patients admitted to Brescia Civic Hospital, were tested for SARS-CoV-2 positivity and molecularly characterized.
Infect Ecol Epidemiol
December 2024
Institute for Globally Distributed Open Research and Education (IGDORE), Karachi, Pakistan.
This article investigates the escalating occurrence of zoonotic diseases in Africa, attributing their spread to climate change and human activities. Africa's unique combination of biodiversity, reliance on animal husbandry, and swift urbanization heightens its susceptibility. Climate change disrupts ecosystems and animal habitats, intensifying human-wildlife interactions.
View Article and Find Full Text PDFChina CDC Wkly
November 2024
National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
What Is Already Known About This Topic?: A substantial proportion of people living with human immunodeficiency virus (PLWH) remain unaware of their infection status. Contact tracing serves as an effective public health tool for identifying human immunodeficiency virus (HIV) infections and supports progress toward achieving the 95-95-95-95 goals.
What Is Added By This Report?: An egocentric contact tracing study conducted in Yunnan, China, between January 2022 and June 2024 enrolled 1,981 index cases, of whom 314 (15.
Math Biosci Eng
October 2024
Computer and Information Science and Engineering Department, University of Florida, Gainesville, FL 32611, USA.
We present an individual-level probabilistic model to evaluate the effectiveness of two traditional control measures for infectious diseases: the isolation of symptomatic individuals and contact tracing (plus subsequent quarantine). The model allows us to calculate the reproduction number and the generation-time distribution under the two control measures. The model is related to the work of Fraser et al.
View Article and Find Full Text PDFBMC Infect Dis
December 2024
HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Background: The uptake of HIV partner status notification remains limited in low- and lower-middle-income countries. This mixed-methods systematic review aims to summarize the barriers and facilitators of HIV partner status notification in these settings.
Methods: We searched PubMed, Embase, CINAHL, PsychINFO, Scopus, and Web of Science from January 01, 2000, to August 31, 2023, for empirical qualitative and quantitative studies.
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