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Progressive macrographia for block letter writing: A case study.

Cortex

November 2021

Department of Neuroscience & Padova Neuroscience Center, University of Padova, Padova, Italy; IRCCS San Camillo Hospital, Venice, Italy. Electronic address:

"Macrographia", a relatively rare symptom generally following cerebellar diseases, consists of an abnormally large handwriting. The case reported in the present investigation shows several outstanding features. First, it is of the progressive variety, letters increase in size as one goes through the word towards the lower-right portion of space.

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Two patients with slowly progressive visuospatial impairment demonstrated a peculiar type of visuoconstructive deficit. The most prominent manifestation appeared when handling kanji (logogram) characters and other figurative patterns. The patients showed pure agraphia for complex kanji but not for kana (syllabogram) or Arabic numerals.

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An 81-year-old right-handed woman was admitted because of acute dysarthria and left hemiparesis. She had lived herself without aids until the admission. On neurological examination she was confused and disoriented.

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Peculiar aspects of reading and writing performances in patients with olivopontocerebellar atrophy.

Percept Mot Skills

April 2002

Dipartimento di Fisiologia e Patologia Generale, U.C.O. di Clinica Neurologica, Università degli Studi di Trieste, Italy.

Olivopontocerebellar atrophy (OPCA) is a still debated condition, of which motor disruption is the most common feature. A high incidence of associated mood disorders may exist, but there are few studies on concomitant cognitive impairment. Our aim was to assess whether there is reading and writing disruption in olivopontocerebellar atrophy (OPCA).

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We report a 60-year-old right-handed Japanese man who showed an isolated persistent typing impairment without aphasia, agraphia, apraxia or any other neuropsychological deficit. We coined the term 'dystypia' for this peculiar neuropsychological manifestation. The symptom was caused by an infarction in the left frontal lobe involving the foot of the second frontal convolution and the frontal operculum.

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