Background: Some patients with FND and FEVD cannot re-establish walking ability with standard treatment alone.
Cases: Novel invasive treatment of FEVD trialed in three females, aged 19, 30 and 33 years with >18 month history of FND. None could walk and all were wheelchair-dependent needing home carers. Standard treatment plus novel step-wise escalation of invasive "intervention+" was individually tailored to correct FEVD; functional electrical stimulation, botulinum toxin injections, tibial nerve block, serial casting, and for Case 3, manipulation under anesthetic and surgical tendon lengthening. All regained walking ability and discontinued carers. Case 1 resumed dancing and Case 3 returned to employment. Improvements were largely maintained at 3 and 6 month follow-up.
Conclusions: As a last resort, invasive adjuncts may be considered in a very small proportion of FND patients who fail to regain walking ability with standard treatment alone and reach a "dead end" where no further progress is feasible.
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http://dx.doi.org/10.1002/mdc3.13264 | DOI Listing |
Front Neurol
January 2025
IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
Body awareness (BA) is a complex multi-dimensional construct that refers to the subject's ability to consciously perceive and integrate sensory and proprioceptive information related to the position, movement, and balance of one's own body and body parts. Since it involves multiple brain regions and include different functional networks, it is very often affected by cerebrovascular damage such as stroke. Deficits in the ability to monitor our actions and predict their consequences or recognize our body parts and distinguish them from those of others may emerge after stroke.
View Article and Find Full Text PDFSci Rep
January 2025
Neurorehabilitation Research Center, Kio University, 4-2-2 Umaminaka, Kitakatsuragi-gun, Koryo, Nara, 635-0832, Japan.
In post-stroke persons, temporal gait asymmetry (TGA) during comfortable gait involves a combination of pure impairments and compensatory strategies. In this study, we aimed to differentiate between pure impairments and compensatory strategies underlying TGA in post-stroke individuals and identify associated clinical factors. We examined 39 post-stroke individuals who participated in comfortable walking speed (CWS) and rhythmic auditory cueing (RAC).
View Article and Find Full Text PDFSci Rep
January 2025
Razak Faculty of Technology and Informatics, Universiti Teknologi Malaysia, 54100, Kuala Lumpur, Malaysia.
As global populations age, ensuring the mobility safety of elderly individuals has become a prominent concern, highlighting the need for innovative designs in assistive products for seniors. This study aims to offer a scientific and practical design methodology for mobility aid designers, validated through the design of a walker for elderly users. To begin, potential user needs for walkers were identified using User Journey Mapping, with these needs categorized through the Kano model to establish a structured hierarchy of design requirements.
View Article and Find Full Text PDFNano Lett
January 2025
Guangxi Key Laboratory of Calcium Carbonate Resources Comprehensive Utilization, College of Materials and Chemical Engineering, Hezhou University, Hezhou City 542899, China.
In nature, animals can realize multimodal movements such as walking, climbing, and jumping through transformation in locomotor gaits or form for survival, which is highly desired for untethered flexible actuators yet remains challenging. Here, we propose a robust self-healing multimodal actuator enabled by noncovalent assembled nanostructures with elaborate regulation of multistage responsive behaviors. Owing to the dynamic interfacial design between multiple components, the stimulus can be accurately delivered through a "light-heat-force release" pathway, endowing the actuator with diverse motion capabilities and desired jumping ability (27 cm, 34 times body length).
View Article and Find Full Text PDFNeurol Sci
January 2025
Department of Physiotherapy, Middle East University, Airport Road, Amman, 11831, Jordan.
Background: Gait impairments are one of the popular consequences of spinal cord injury (SCI). Acute intermittent hypoxia (AIH) is an innovative treatment that has recently been used to enhance motor function in patients with neurological conditions. This review aims to examine the effects of AIH on gait post-SCI, verify who most likely would benefit from the treatment, and recognize the best treatment protocol, if possible.
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