Open innovation is a young arena in research that is fascinating the attention of a growing number of scholars. However, there are not enough studies that investigate open innovation performance. The pharmaceutical industry with the most Research and Development (R&D) intensity has been targeted by this new paradigm. This study explores the effect of entrepreneurial orientation on open innovation performance, considering the mediating role of desorptive capacity, which is defined as the firm's capability to recognize outward technology transfer opportunities and to facilitate it. We use structural equation modeling to examine the hypotheses on a dataset from 100 Iranian pharmaceutical manufacturers in 2018. The results of the study support our conceptual model. Our findings indicate that a firm's entrepreneurial orientation and desorptive capacity have a positive effect on its open innovation performance. Moreover, desorptive capacity has a mediating effect in the relation of entrepreneurial orientation and open innovation performance. This denotes that our new model contributes to the concept of desorptive capacity in the context of open innovation.
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http://dx.doi.org/10.22037/ijpr.2019.15427.13092 | DOI Listing |
JAMA Netw Open
January 2025
Ronald O. Perelman Department of Emergency Medicine, New York University Langone Health, New York.
Importance: Increasing underrepresented in medicine (URIM) physicians among historically underserved communities helps reduce health disparities. The concordance of URIM physicians with their communities improves access to care, particularly for American Indian and Alaska Native, Black, and Hispanic or Latinx individuals.
Objectives: To explore county-level racial and ethnic representation of US internal medicine (IM) residents, examine racial and ethnic concordance between residents and their communities, and assess whether representation varies by presence of academic institutions or underserved settings.
Chem Sci
January 2025
Instituto de Carboquímica (ICB-CSIC) C/Miguel Luesma Castán 4 E-50018 Zaragoza Spain
Fluorescent nitrogen-doped carbon dots (N-GQDs) with long-wavelength emission properties are of increased interest for technological applications. They are widely synthesized through the solvothermal treatment of graphene oxide (GO) using ,-dimethylformamide (DMF) as a cleaving and doping agent. However, this process simultaneously generates undesired interfering blue-emissive by-products.
View Article and Find Full Text PDFMetabol Open
March 2025
Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa, 3886, South Africa.
Dyslipidemia is a prominent pathological feature responsible for oxidative stress-induced cardiac damage. Due to their high antioxidant content, dietary compounds, such as aspalathin and sulforaphane, are increasingly explored for their cardioprotective effects against lipid-induced toxicity. Cultured H9c2 cardiomyoblasts, an in vitro model routinely used to assess the pharmacological effect of drugs, were pretreated with the dietary compounds, aspalathin (1 μM) and sulforaphane (10 μM) before exposure to palmitic acid (0.
View Article and Find Full Text PDFCureus
December 2024
Department of Conservative Dentistry and Endodontics, The Oxford Dental College, Bengaluru, IND.
Preserving pulp vitality in developing permanent teeth is paramount. This approach facilitates continued root formation, ultimately leading to apical closure, enhanced root strength, and improved overall tooth integrity. This case report details the management of a 17-year-old female patient presenting with dental caries on the right permanent maxillary molar.
View Article and Find Full Text PDFCureus
December 2024
Anesthesiology, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Bone marrow aspiration is an essential procedure for diagnosing hematological conditions and therapeutic applications, such as bone marrow aspirate concentrate (BMAC) therapy for non-union of bones. This report presents a case of a 35-year-old male with femoral non-union treated with BMAC, requiring the collection of a large bone marrow aspirate volume. A novel, low-cost modification to the standard bone marrow aspiration apparatus was developed using components from an intravenous (IV) drip set, including a rubber bulb connector and a luer lock connector.
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