Introduction: Pedestrian safety is a major concern as traffic crashes are the leading cause of fatalities and injuries for commuters. Traffic safety research in the past has developed various strategies to counteract traffic crashes, including the safety performance function (SPF). However, there is still a need for research dedicated to enhancing the SPF for pedestrians from perspectives of methodological framework and data input. To fill this gap, this study aims to add to the current SPF development practice literature by focusing on pedestrian-involved collisions, while considering the typical vehicle ones as well.
Methods: First, bivariate models are used to account for the common unobserved heterogeneity shared by the pedestrian- and vehicle-related crashes at the same intersections. Second, variable importance ranking technique is used, along with correlation analysis, to determine mode-specific feature input. Third, the exposure information for both modes, annual pedestrian count, and annual daily vehicles traveled are used for model development. Fourth, a recent Bayesian inference approach (integrated nested Laplace approximation (INLA)) was adopted for bivariate setting. Finally, different evaluation criteria are used to facilitate comprehensive model assessment.
Results: The results reveal different statistically significant factors contributing to each of the modes. The offset intersection provides better safety performance for both pedestrians and drivers as compared to other intersection designs. The model findings also corroborate the sensibility of using the bivariate models, rather than the separate univariate ones. Practical Applications: The study shows that pedestrians are more vulnerable to various intersection features such as left-turn channelization, intersection control, urban and rural population group, presence of signal mastarm on the cross-street, and mainline average daily traffic. Greater focus should be directed toward such intersection features to improve pedestrian safety.
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http://dx.doi.org/10.1016/j.jsr.2021.05.008 | DOI Listing |
Phytochem Anal
December 2024
School of Food and Biological Engineering, Henan University of Science and Technology, Luoyang, Henan, China.
Introduction: The extraction of DNA is the basis of molecular biology research. The quality of the extracted DNA is one of the key factors for the success of molecular biology experiments.
Objective: To select a suitable DNA extraction method for Chinese medicinal herbs and seeds.
Adv Sci (Weinh)
December 2024
New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Radiodynamic therapy that employs X-rays to trigger localized reactive oxygen species (ROS) generation can tackle the tissue penetration issue of phototherapy. Although calcium tungstate (CaWO) shows great potential as a radiodynamic agent benefiting from its strong X-ray absorption and the ability to generate electron-hole (e-h) pairs, slow charge carrier transfer and fast e-h recombination greatly limit its ROS-generating performance. Herein, via a one-pot wet-chemical method, oxygen vacancy-rich amorphous/crystalline heterophase CaWO nanoparticles (Ov-a/c-CaWO NPs) with enhanced radiodynamic effect are synthesized for radiodynamic-immunotherapy of cancer.
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
Department of Plastic and Reconstructive Surgery, Senior Department of Burns and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Background: Hypertrophic scar (HS) is a fibroproliferative disorder resulting from abnormal healing of skin tissue after injury. Although various therapies are currently employed in clinical to treat HSs, there is no widely accepted standard therapy. Micro-plasma radiofrequency (MPR) and autologous chyle fat grafting are emerging treatments for this condition, and they have demonstrated promising therapeutic outcomes in clinical applications.
View Article and Find Full Text PDFScand J Gastroenterol
December 2024
Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Background And Study Aims: Diffuse infiltrative gastric cancer can be difficult to diagnose owing to a lack of endoscopic features in the superficial mucosa. Moreover, a forceps biopsy may not reveal a pathological diagnosis. We aimed to evaluate the diagnostic yield and safety of endoscopic mucosal resection (EMR) and 'open-lid submucosal biopsy', a technique wherein EMR followed by biopsy of the ulcer floor is performed for a pathological diagnosis.
View Article and Find Full Text PDFBMC Vet Res
December 2024
Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
Background: The inclusion of sustainable protein sources in poultry feed has become essential for improving animal welfare in livestock production. Black soldier fly larvae are a promising solution due to their high protein content and sustainable production. However, most research has focused on fast-growing poultry breeds, while the effects on native breeds, such as the Bianca di Saluzzo, are less explored.
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