Cowper's gland hyperplasia: A potential pitfall at MRI of the prostate.

Clin Imaging

Departments of Diagnostic Radiology, Oregon Health & Science University, Portland, OR, United States of America. Electronic address:

Published: November 2021

AI Article Synopsis

  • A multicenter study looked at MRI findings in five patients with a masslike lesion in the genitourinary diaphragm linked to prostate cancer investigations.
  • The lesions were 1.3 to 3.0 cm, encapsulated, and showed low to intermediate T2 signal intensity, with biopsies revealing benign Cowper's gland tissue.
  • This condition can lead to misdiagnosis as benign prostatic hyperplasia or prostate cancer spread, highlighting the need for accurate identification of Cowper's gland hyperplasia in MRIs.

Article Abstract

MRI features are presented in a multicenter retrospective series of five patients with a unilateral masslike lesion seen in the genitourinary diaphragm at MRI performed for known or suspected prostate cancer. In all cases, the lesion appeared as an encapsulated 1.3 to 3.0 cm mass of heterogeneous low or intermediate T2 signal intensity in the genitourinary diaphragm, and targeted biopsy demonstrated benign Cowper's gland tissue. This entity is a potential imaging pitfall that could result in a diagnosis of an exophytic nodule of benign prostatic hyperplasia or local spread of prostate cancer. We present these cases to facilitate correct identification of Cowper's gland hyperplasia as an occasional finding at MRI of the prostate.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331467PMC
http://dx.doi.org/10.1016/j.clinimag.2021.07.027DOI Listing

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