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Dairy cow performance and nutrient utilization when offered high or low digestibility grass silages at 2 levels of total diet crude protein.
JDS Commun
January 2025
Agri-Food and Biosciences Institute, Sustainable Agri-Food Sciences Division, Large Park, Hillsborough, County Down BT26 6DR, Northern Ireland.
The hypothesis of this study was that grass silage digestibility would influence the response of dairy cows offered diets differing in CP content. Thirty-two mid-lactation Holstein dairy cows were used in a 2-period (21-d adaption phase, 7-d measurement phase), partially balanced change-over experiment. Four treatments were organized in a 2 × 2 factorial arrangement, comprising 2 grass silages differing in digestible OM in the DM (D-value; 748 and 668 g/kg DM, high-D and low-D, respectively) and 2 total diet CP levels (target 145 and 175 g/kg DM, high CP and low CP, respectively).
View Article and Find Full Text PDFOxylipin dynamics in dairy cows during clinical ketosis and after treatment with niacin and flunixin meglumine.
JDS Commun
January 2025
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824.
Dairy cows with clinical ketosis (CK) exhibit metabolic changes, including intense adipose tissue (AT) lipolysis and systemic insulin resistance, that increase plasma BHB and free fatty acids (FFA). Cows with CK also have systemic inflammation, predisposing them to inflammatory and infectious diseases. This inflammatory process is modulated in part by oxidized fatty acids (oxylipins) that regulate all aspects of inflammation.
View Article and Find Full Text PDFWeighted single-step genomic best linear unbiased predictor enhances the genomic prediction accuracy for milk citrate predicted by milk mid-infrared spectra of Holstein cows in early lactation.
JDS Commun
January 2025
TERRA Teaching and Research Center, University of Liège, Gembloux Agro-Bio Tech (ULiège-GxABT), 5030 Gembloux, Belgium.
Previous studies have shown that milk citrate predicted by milk mid-infrared (MIR) spectra is strongly affected by a few genomic regions. This study aimed to explore the effect of weighted single-step GBLUP on the accuracy of genomic prediction (GP) for MIR-predicted milk citrate in early-lactation Holstein cows. A total of 134,517 test-day predicted milk citrate collected within the first 50 DIM on 52,198 Holstein cows from the first 5 parities were used.
View Article and Find Full Text PDFProtected palmitic acid to mitigate milk fat depression in grazing Holstein cows in the Mexican Highlands.
Arch Anim Nutr
January 2025
Posgrado en Producción Animal. Departamento de Zootecnia, Universidad Autónoma Chapingo, Texcoco, México.
The and isomers of conjugated linoleic acid (CLA) are associated with anticancer and lipolytic effects in tissues, respectively, but in lactating cows, the latter isomer reduces the milk fat concentration, a detrimental aspect for the dairy industry, as it reduces the yield of milk derivatives. Therefore, the objective of this study was to evaluate the effect of providing protected palmitic acid (PA) to grazing lactating Holstein cows supplemented with soybean oil as a source of conjugated linoleic acid, on milk production, fat concentration and mitigation of milk fat depression. Nine multiparous Holstein cows were used, distributed in three groups of three cows each, with initial means of days in milk, live weight, milk production, and number of calvings: 124 ± 16 days, 494 ± 53 kg, 20.
View Article and Find Full Text PDFReal-world safety evaluation of brivaracetam: insights from the US FDA adverse event reporting system.
Expert Opin Drug Saf
January 2025
Shaoxing Yuecheng District People's Hospital, Shaoxing, China.
Background: Brivaracetam (BRV) is a novel drug for the treatment of epilepsy. This study aimed to detect and characterize adverse events (AEs) associated with BRV from the first quarter of 2016 to the second quarter of 2024 using the U.S.
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