Life-threatening COVID-19 pneumonia follows an exaggerated immune response to SARS-CoV-2. pGSN levels fall after SARS-CoV-2 infection. Rhu-pGSN improves outcomes in models of inflammation. In an intubated patient with critical COVID-19 pneumonia and progressive hypoxemia despite standard care, improvement became evident during rhu-pGSN infusions with full recovery within a few weeks.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353968 | PMC |
| http://dx.doi.org/10.1016/j.clinpr.2021.100088 | DOI Listing |
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