AI Article Synopsis
- - A new method using CBr was created to synthesize imidazo[1,5-a]heterocycles from pyridin-2-ylmethanamines and aldehydes through a [4 + 1] dehydrocyclization reaction.
- - This process is practical and allows for a variety of starting materials and functional groups.
- - The reaction conditions are mild, making it an accessible option for chemists.
Article Abstract
A CBr mediated [4 + 1] dehydrocyclization was developed for the synthesis of imidazo[1,5-a]heterocycles from pyridin-2-ylmethanamines and aldehydes. This method was highly practical with the advantages of wide substrate scope, functional group tolerance, and mild reaction conditions.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358950 | PMC |
| http://dx.doi.org/10.1021/acsomega.1c02181 | DOI Listing |
Publication Analysis
Top Keywords
cbr mediated
8
mediated dehydrocyclization
8
imidazo[15-a]heterocycles pyridin-2-ylmethanamines
8
pyridin-2-ylmethanamines aldehydes
8
dehydrocyclization synthesis
4
synthesis functionalized
4
functionalized imidazo[15-a]heterocycles
4
aldehydes cbr
4
dehydrocyclization developed
4
developed synthesis
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!