AI Article Synopsis
- The traditional gold-standard for treating ocular surface squamous neoplasia (OSSN) has been surgical excision, but it comes with risks like unfavorable outcomes and high recurrence rates if margins aren't clear.
- In recent years, topical chemotherapy options such as 5-fluorouracil, interferon α-2b, and mitomycin C have emerged as effective treatments that can reduce the need for surgery and potentially have fewer long-term effects.
- Anterior segment high-resolution optical coherence tomography is a valuable diagnostic and monitoring tool for OSSN, aiding both surgical and medical treatment approaches.
Article Abstract
The gold-standard treatment for ocular surface squamous neoplasia (OSSN) has traditionally been surgical excision with wide margins and a no-touch technique. However, surgery may be associated with several unfavourable sequelae, as well as significant recurrence rates if margins are positive. In recent years, topical chemotherapy with 5-fluorouracil, interferon α-2b and mitomycin C have emerged as valuable agents capable of effectively treating OSSN with varying adverse effects. These medical treatment options usually present additional costs to the patient but can allow patients to avoid surgery with fewer long-term effects. Anterior segment high-resolution optical coherence tomography is an excellent tool for diagnosing and monitoring OSSN and can be a useful aid for both surgical and medical treatments of OSSN.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317100 | PMC |
| http://dx.doi.org/10.1136/bmjophth-2021-000842 | DOI Listing |
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