AI Article Synopsis
- Deep brain stimulation (DBS) is a treatment that was first approved in the U.S. in 1997, and its technology has improved a lot since then.
- The study looked at 34 articles about DBS from 2008 to 2020 and found that the overall complication rate for patients was 16.7%.
- The results show that complications have become less common in recent years, so it's important to keep finding ways to make the surgery safer.
Article Abstract
Background: Deep brain stimulation (DBS) was first approved by the United States Food and Drug Administration in 1997. Although the fundamentals of DBS remain the same, hardware, software, and imaging have evolved significantly.
Objective: To test our hypothesis that the aggregate complication rate in the medical literature in the past 12 years would be lower than what is often cited based on early experience with DBS surgery.
Methods: PubMed, PsycINFO, and EMBASE were queried for studies from 2008 to 2020 that included patients treated with DBS from 2007 to 2019. This yielded 34 articles that evaluated all complications of DBS surgery, totaling 2249 patients.
Results: The overall complication rate in this study was 16.7% per patient. There was found to be a systemic complication rate of 0.89%, intracranial complication rate of 2.7%, neurological complication rate of 4.6%, hardware complication rate of 2.2%, and surgical site complication rate of 3.4%. The infection and erosion rate was 3.0%.
Conclusion: This review suggests that surgical complication rates have decreased since the first decade after DBS was first FDA approved. Understanding how to minimize complications from the inception of a technique should receive more attention.
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| http://dx.doi.org/10.1093/ons/opab261 | DOI Listing |
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