AI Article Synopsis
- The study assessed the effectiveness of probiotics alongside scaling and root planning (SRP) for treating periodontitis by analyzing data from multiple research databases.
- The meta-analysis included 24 randomized controlled trials, showing significant improvements in clinical attachment level, probing pocket depth, and bleeding on probing after 3 months of probiotic treatment with SRP.
- While the short-term results were positive, indicating that probiotics can enhance periodontal health, the long-term benefits beyond 3 months need further investigation.
Article Abstract
Objectives: To evaluate the efficacy of probiotics as an adjunctive therapy to scaling and root planning treatment (SRP) in the management of periodontitis.
Methods: PubMed, Embase, Web of science, SCOPUS and the Cochrane library were systematically searched to identify eligible studies. Stata 12.0 software was used to calculate the weighted mean differences (WMD) and 95% confidential interval (CI). The primary outcomes were clinical attachment level (CAL), probing pocket depth (PPD) and bleeding on probing (BOP).
Results: Twenty-four randomized controlled trials (RCT) were included in the meta-analysis. The pooled results showed CAL gain (WMD: 0.20, 95% CI 0.09 to 0.31), PPD reduction (WMD: -0.31, 95% CI -0.52 to -0.10) and BOP reduction (WMD: -2.98, 95% CI -4.70 to -1.26) in the SRP+ probiotics group were significantly improved compared to control group at 3 months follow-up, but no significant difference was observed at 6 months. In addition, the probiotics administration could improve Plaque index (WMD: -0.30, 95% CI -0.59 to -0.05) and Gingival index (WMD: -0.46, 95% CI -0.71 to -0.21) at short term.
Conclusions: The results support the clinical efficacy of probiotics as an adjunctive therapy to SRP in the management of periodontitis at least 3 months follow-up. Within the limits of the evidence, the long-term efficacy needs to further confirm.
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| http://dx.doi.org/10.1016/j.jebdp.2021.101547 | DOI Listing |
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