The content of ascorbic acid and alpha-tocopherol was found to be decreased in the blood of rats which had suffered an emotional pain stress. Preadaptation of the animals to hypoxia did not change the level of ascorbic acid, but it was valuable with respect to alpha-tocopherol. The emotional pain stress in the presence of adaptation to hypoxia induced in the animals reduction of the blood levels of both vitamins similar to that in the controls. The synthetic antioxidant ionol diminished stress-induced hypovitaminosis of ascorbic acid and completely prevented reduction of alpha-tocopherol level in the blood of rats after the stress.

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