Objectives: Irritability is a transdiagnostic symptom in developmental psychopathology, conceptualized as a low threshold for frustration and increased proneness to anger. While central to emotion regulation, there is a vital need for empirical studies to explore the relationship between irritability and underlying physiological mechanisms of cardiovascular arousal.
Methods: We examined the relationship between irritability and cardiovascular arousal (i.e., heart rate [HR] and heart rate variability [HRV]) in a transdiagnostic sample of 51 youth (M = 12.63 years, SD = 2.25; 62.7% male). Data was collected using the Empatica E4 during a laboratory stop-signal task. In addition, the impact of motion activity, age, medication, and sleep on cardiovascular responses was explored.
Results: Main findings showed that irritability was associated with increased HR and decreased HRV during task performance.
Conclusions: Findings support the role of peripheral physiological dysregulation in youth with emotion regulation problems and suggest the potential use of available wearable consumer electronics as an objective measure of irritability and physiological arousal in a transdiagnostic sample of youth.
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http://dx.doi.org/10.1002/mpr.1890 | DOI Listing |
Sci Rep
January 2025
Cognitive Neuroanatomy Lab, INCC UMR 8002, CNRS, Université Paris Cité, Paris, France.
Functional connectivity holds promise as a biomarker of schizophrenia. Yet, the high dimensionality of predictive models trained on functional connectomes, combined with small sample sizes in clinical research, increases the risk of overfitting. Recently, low-dimensional representations of the connectome such as macroscale cortical gradients and gradient dispersion have been proposed, with studies noting consistent gradient and dispersion differences in psychiatric conditions.
View Article and Find Full Text PDFJ Affect Disord
January 2025
Centre for Psychosocial Health, The Education University of Hong Kong, Hong Kong; Department of Psychology, The Education University of Hong Kong, Hong Kong. Electronic address:
Objective: The current study compared symptom networks between individuals exhibiting resilience and non-resilience trajectories of adaptation two years after the COVID-19 outbreak.
Method: A population-representative sample (N = 906) reported symptoms of anxiety and depression in February-July 2020 (T1), March-August 2021 (T2), and September 2021-February 2022 (T3), as well as symptoms of post-traumatic stress disorder (PTSD) and adjustment disorder (AD) at T3. After differentiating between individuals with resilience and non-resilience trajectories using growth mixture modeling, network analyses were conducted to investigate group differences in T3 network symptoms (undirected and directed).
Clin Child Fam Psychol Rev
January 2025
School of Psychology, The University of Sydney, Sydney, NSW, 2006, Australia.
This meta-analytic review examined irritability across childhood and adolescence as it relates to symptoms of common mental health disorders in these periods. Of key interest was whether the relationship between irritability and symptom severity varies according to symptom domain. This was tested at the level of broad symptom dimensions (internalizing versus externalizing problems) as well as discrete diagnostic domains (e.
View Article and Find Full Text PDFTrauma Violence Abuse
January 2025
Department of Psychology, University of Wisconsin-Madison, Madison, WI, USA.
Although sexual violence (SV) has been hypothesized to increase shame, the relationship between SV and shame has not been quantified. Addressing this gap is essential for developing targeted interventions for survivors, as shame is a transdiagnostic risk factor for numerous forms of psychopathology and a barrier to service-seeking. This meta-analysis first examines whether individuals exposed to SV demonstrate higher shame than individuals who reported no SV exposure.
View Article and Find Full Text PDFBr J Clin Psychol
January 2025
Centre for Sleep Science, School of Psychological Science, University of Western Australia, Crawley, Western Australia, Australia.
Objectives: Despite evidence supporting sleep's role in the development and maintenance of depression, mechanisms underlying this association in young people are less established. Negative interpretation bias (the tendency to interpret ambiguous situations negatively) and repetitive negative thinking (RNT) are important candidate mechanisms. Whilst negative interpretation bias is implicated in depression development, it is a transdiagnostic process and may result from insomnia.
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