AI Article Synopsis
- Therapeutic plasma exchange (TPE) is a key apheresis technique used to treat various health issues, especially in critical conditions related to the kidneys, nervous system, and blood.
- TPE operates mainly through centrifugal separation or membrane filtration to remove disease-causing substances from the plasma.
- The review covers the fundamentals of TPE, its technology, and clinical applications in intensive care, along with guidelines from the American Society for Apheresis.
Article Abstract
Therapeutic plasma exchange (TPE) is frequently the most common Apheresis Medicine technique used for extracorporeal therapy of a wide variety of renal, neurological, hematological, and other clinical indications. Many of these clinical indications require intensive care during critical illness. Conventional TPE uses one of two main technical methods to achieve the goal of removing known disease mediators from the plasma: using centrifugal forces to separate and remove components of blood, or a membrane filtration method that separates plasma from the cellular components of blood. The following review discusses the basic principles of TPE, the technological aspects, and relevant clinical scenarios encountered in the intensive care unit, including relevant guidelines and recommendations from the American Society for Apheresis.
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| http://dx.doi.org/10.1053/j.ackd.2021.03.005 | DOI Listing |
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