Purpose: To estimate the surface dose in diagnostic radiology in real time based on the relationship between the incident air kerma and the surface dose.
Methods: The air kerma for 20 X-ray beams with tube voltages of 50-140 kV and a half-value layer (HVL) of 2.27-9.65 mm Al was measured using an ionization chamber. The beam quality was classified based on the quality indexes (QIs) of 0.4, 0.5, and 0.6, which are defined as the ratio of the effective energy to the maximum energy corresponding to the tube potential. The surface dose for 20 X-ray beams was evaluated based on the measured air kerma, backscatter factor, and ratio of the mass-energy absorption coefficients of water to air, which were calculated using the Monte Carlo method. Finally, the relationship between the air kerma and the surface dose was investigated for X-ray beams with the specific QI values.
Results: The surface dose at a water phantom was represented by a linear approximation of R > 0.98, with the air kerma, regardless of the X-ray beam quality. The surface dose estimated based on a linear approximation with the air kerma indicated an agreement within 8% with that evaluated by the chamber measurements at HVL > 3.4 mm Al.
Conclusion: It is possible to estimate the surface dose in real time using the linear relationship between the incident air kerma and the surface dose regardless of the X-ray beam quality by accepting ±10% uncertainty in the surface dose estimation.
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http://dx.doi.org/10.1016/j.ejmp.2021.07.031 | DOI Listing |
Bioorg Chem
January 2025
Department of Chemistry, St Berchmans College (Autonomous), Changanassery, Kerala 686101, India; Centre for Theoretical and Computational Chemistry, St Berchmans College (Autonomous), Changanassery, Kerala 686101, India. Electronic address:
In this study, three novel derivatives of benzo[b]thiophene-2-carbaldehyde (BTAP1, BTAP2, and BTAP3) were successfully synthesized and comprehensively characterized using spectroscopic techniques including FTIR, UV-VIS, HNMR, and CNMR. Thermal analysis through TGA and DTA demonstrated remarkable thermal stability with a maximum threshold at 270 °C. Spectroscopic investigations revealed π → π* transitions in all compounds, attributed to the conjugated system comprising benzothiophene rings connected to bromophenyl/ aminophenyl/phenol rings via α, β-unsaturated ketone bridges.
View Article and Find Full Text PDFFront Allergy
January 2025
Laboratory for Clinical Immunology and Molecular Genetics, University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia.
The basophil activation test (BAT) has become a major cellular test for evaluating the allergenic activity of specific IgEs. The impact of the BAT is due to the ability of blood basophil granulocytes to present IgE on the high-affinity FcRI receptor and to mirror the mast cell response that elicits an acute allergic reaction. The BAT proved to be able to identify allergic patients at risk of reacting to a low dose of the allergen and/or developing life-threatening reactions and thus can significantly improve the current management of allergic patients.
View Article and Find Full Text PDFPostepy Dermatol Alergol
December 2024
Department of Internal Medicine, Angiology and Physical Medicine in Bytom, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Introduction: Diabetic foot syndrome (DFS) a severe complication of diabetes which can result in ulcers, infections, or tissue damage in the feet.
Aim: To compare the treatment effectiveness in patients with DFS using local O therapy depending on the O concentration.
Material And Methods: The study included 50 patients, 24 male and 26 female ones, in the age range between 39 and 84 years, with DFS.
Int J Pharm
January 2025
University of Applied Sciences and Arts Northwest. Switzerland, School of Life Sciences, Institute of Pharma Technology, Hofackerstr. 30 CH-4132 Muttenz, Switzerland. Electronic address:
In recent years, deep eutectic solvents (DESs) with their outstanding solubilization properties have emerged as strong candidates for oral enabling formulations of poorly soluble drugs. This study explores the use of drug-based therapeutic DESs (THEDESs) to solubilize a poorly soluble compound with the aim of providing a fixed-dose combination of two complementary therapeutic agents. Specifically, potential anticancer effects of ibuprofen (IBU) are harnessed in a novel type of THEDES to dissolve higher amounts of abiraterone acetate (AbAc), an antitumor agent.
View Article and Find Full Text PDFTrop Anim Health Prod
January 2025
Department of Agroindustrial Science and Technology, Federal University of Pelotas, Rio Grande Do Sul, Brazil.
During the harvest of Ilex paraguariensis, approximately 2-5 tons per hectare of thick stems are left on the soil surface. The outer portion of these stems, referred to as the coproduct, constitutes 30% of the total residue mass. Although this coproduct has been partially characterized in terms of its phytochemical profile, its technological applications remain unexplored.
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