AI Article Synopsis
- Ulcerative sarcoidosis is a rare form of skin condition characterized by painful, necrotic yellow plaques appearing on various body parts, including the legs, face, and arms.* -
- A 60-year-old woman had severe symptoms for over 20 years that didn't improve with traditional treatments like hydroxychloroquine and methotrexate.* -
- After four months of treatment with adalimumab, along with pentoxifylline and prednisone, she experienced significant improvement in her skin condition.*
Article Abstract
Ulcerative sarcoidosis is a rare variant of cutaneous sarcoidosis that may present as ulceration with necrotic yellow plaques on the lower extremities, face, arms, trunk, or genital area. Adalimumab, a human monoclonal anti-TNF antibody, is an emerging treatment for recalcitrant cutaneous sarcoidosis. We describe severe ulcerative sarcoidosis in a 60-year-old woman with chronic ulcerative necrobiosis lipoidica-like plaques on her left arm for over 20 years. Her condition had not responded to previous treatments with hydroxychloroquine, methotrexate, and sulfasalazine. After a four-month course of adalimumab therapy in addition to pentoxifylline and prednisone with taper, the patient had significant improvement in her skin disease.
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| http://dx.doi.org/10.5070/D327654058 | DOI Listing |
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