Drosophila Satellite Repeats at the Intersection of Chromatin, Gene Regulation and Evolution.

Prog Mol Subcell Biol

Department of Biological Sciences, Wayne State University, Detroit, MI, USA.

Published: September 2021

AI Article Synopsis

  • Satellite repeats are parts of the DNA in many complex living things, like fruit flies, and were once thought to be useless.
  • Scientists studied these repeats in fruit flies and found they can actually influence how genes work and affect how species develop over time.
  • The research shows that satellite repeats are important for understanding evolution and how different species of flies might change from each other.

Article Abstract

Satellite repeats make up a large fraction of the genomes of many higher eukaryotes. Until recently these sequences were viewed as molecular parasites with few functions. Drosophila melanogaster and related species have a wealth of diverse satellite repeats. Comparative studies of Drosophilids have been instrumental in understanding how these rapidly evolving sequences change and move. Remarkably, satellite repeats have been found to modulate gene expression and mediate genetic conflicts between chromosomes and between closely related fly species. This suggests that satellites play a key role in speciation. We have taken advantage of the depth of research on satellite repeats in flies to review the known functions of these sequences and consider their central role in evolution and gene expression.

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Source
http://dx.doi.org/10.1007/978-3-030-74889-0_1DOI Listing

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