Mammography has a crucial role in breast cancer detection. The National Cancer Institute (INCA) estimates that 29.7% of the cancer cases in Brazil are related specifically to the breast. It is necessary to evaluate the mean glandular dose with a new solid-state detector in a digital radiography system, utilizing PMMA phantoms and spacers for different thicknesses. The Selenia Dimensions (Hologic, Bedford) direct radiography (DR) system can perform full-field digital mammographies through digital detectors. This system uses new technologies, such as the digital breast tomosynthesis system (DBT), and employs a sequence of projections acquired over the breast, resulting in images with low contrast. The estimation of breast dose is an important part of mammographic quality control for x-ray mammography. Nevertheless, there are currently no standard protocols for the dosimetry of breast imaging in 3D. Additionally, a x-ray spectra function is crucial to measure a considerable output in x-ray spectrometry. The purpose of this work was to assess the mean glandular dose (MGD) and the spectra in slabs of polymethyl methacrylate (PMMA) and breast equivalent thickness through digital mammography using four experiments: a Hologic Selenia Dimensions mammograph with a solid-state detector; a spectrometer (only for the spectra, in this case); a clinical COMET x-ray tube with a solid-state detector; and the MCNPX code. References recommend that the real environments that work well with digital mammography are in the following tube voltages: 25 kVp; 26 kVp; 28 kVp; 31 kVp and 33 kVp. Taking into account several thicknesses of PMMA, the results of both the MGD in metrological, clinical and simulated cases were in accordance with the references, from 30 mm of PMMA. All the spectra for all cases have indicated good agreement with the references.
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http://dx.doi.org/10.1016/j.apradiso.2021.109862 | DOI Listing |
Ann Anat
December 2024
Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, Perugia 06126, Italy.
Visfatin is an adipokine with mediatory effects on inflammation. It is expressed at low levels in the pig stomach, but its role in the gastrointestinal (GI) tract is not well understood. This study explored visfatin expression and localisation in the stomach and duodenum of piglets fed varying levels of polyphenols derived from olive mill waste extract, known for their antioxidant and immunomodulatory properties.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2024
Faculty of Applied Science, Uplands College of Science and Technology Incorporated (UCSI), Kuala Lumpur 56000, Malaysia.
Environ Mol Mutagen
November 2024
General and Genetic Toxicology, Charles River Laboratories, Ashland, Ohio, USA.
Bioorg Chem
December 2024
Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, People's Republic of China. Electronic address:
Fifteen undescribed phenylpropanoyl phloroglucinol derivatives featuring modified isoprenyl and/or geranyl units (1-15), in conjunction with thirteen known analogues (16-28), were obtained from the glandular hairs of the fruit of Mallotus philippensis. Meanwhile, fourteen pairs of new enantiomers [(±)-1-9, (±)-11-15] were further resolved by chiral purification. Their structures were determined by comprehensive spectroscopic analyses, single-crystal X-ray diffraction experiments and quantum chemical calculations.
View Article and Find Full Text PDFEur J Radiol
December 2024
Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139,7 2695-066, Bobadela LRS, Portugal.
Background: Conventional mammography remains the primary imaging modality for state-of-the-art breast imaging practice and its benefit (both on diagnostic and screening) was largely reported. In mammography, the typical Mean Glandular Dose (MGD) from X-ray radiation to the breast spans, on average, from 1 to 10 mGy, depending on breast thicknesses, percentage of fibroglandular tissue, and on the examination purpose.
Methods: The aim of this narrative review is to describe the extent of radiation risk in X-ray breast imaging and discuss the main steps and parameters (e.
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