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Autoimmune Encephalitis with Antibodies: Anti-NMDAR, Anti-AMPAR, Anti-GQ1b, Anti-DPPX, Anti-CASPR2, Anti-LGI1, Anti-RI, Anti-Yo, Anti-Hu, Anti-CV2 and Anti-GABAAR, in the Course of Psychoses, Neoplastic Diseases, and Paraneoplastic Syndromes.
Diagnostics (Basel)
August 2023
Department of Neurology, Institute of Medical Sciences, University of Opole, 45040 Opole, Poland.
Encephalitis is a condition with a variety of etiologies, clinical presentations, and degrees of severity. The causes of these disorders include both neuroinfections and autoimmune diseases in which host antibodies are pathologically directed against self-antigens. In autoimmune encephalitis, autoantibodies are expressed in the central nervous system.
View Article and Find Full Text PDFClinical analysis of 173 pediatric patients with antibody-mediated autoimmune diseases of the central nervous system: a single-center cohort study.
Front Immunol
May 2023
Department of Neurology, Hunan Children's Hospital, Changsha, China.
Background: Antibody-mediated disorders of the central nervous system (CNS) have seen a gradual rise in their incidence and prevalence. This retrospective observational study aimed to investigate the clinical characteristics and short-term prognosis of children with antibody-mediated CNS autoimmune diseases at Hunan Children's Hospital.
Methods: We collected the clinical data of 173 pediatric patients diagnosed with antibody-mediated CNS autoimmune diseases between June 2014 and June 2021 and analyzed their demographics, clinical features, imaging and laboratory data, treatment, and prognosis.
Anti-Caspr2 encephalitis coexisting with neurosyphilis: a rare case report.
Acta Neurol Belg
October 2023
Department of Neurology, West China Hospital, Sichuan University, No.37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Coexistence of antiCASPR2 autoimmune encephalitis, normotensive hydrocephalus and Alzheimer's disease: when Ockham's razor faces clinical practice.
Neurol Sci
November 2021
Neurology Department, Cruces University Hospital, Plaza Cruces S/N 48903, Barakaldo, Basque Country, Spain.
Possible coexistence of MOG-IgG-associated disease and anti-Caspr2 antibody-associated autoimmune encephalitis: a first case report.
Ther Adv Neurol Disord
October 2020
Department of Neurology, Tangdu Hospital, Air Force Military Medical University, No. 569 Xinsi Road, Xi'an, Shaanxi Province 710038, China.
Myelin oligodendrocyte glycoprotein antibody-associated disease has been proposed as a separate inflammatory demyelinating disease of the central nervous system (CNS) since the discovery of pathogenic antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG). Antibodies targeting contactin-associated protein-like 2 (Caspr2), a component of voltage-gated potassium channel (VGKC) complex, have been documented to be associated with a novel autoimmune synaptic encephalitis with a low incidence. Herein, we reported an adult female with initial presentation of decreased vision in the right eye and subsequent episodes of neuropsychiatric disturbance including hypersomnia, agitation, apatheia, and memory impairment.
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