EasyNanopore: A Ready-to-Use Processing Software for Translocation Events in Nanopore Translocation Experiments.

Langmuir

State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

Published: August 2021

AI Article Synopsis

  • EasyNanopore is a user-friendly software designed for analyzing nanopore molecular translocation experiments, available as an executable file for various operating systems.
  • The software utilizes an adaptive threshold to detect events and employs a multiprocess method to speed up detection.
  • Once events are identified, it extracts key data like duration and amplitude, generating a text file for further analysis, and is capable of handling large-scale experiments efficiently.*

Article Abstract

We developed EasyNanopore which is a ready-to-use software to select the events of a nanopore molecular translocation experiment. The software is released as an executable file with a graphical user interface and provides several versions suitable for different operating systems without installing any running environment to execute it. We use the adaptive threshold which adapts to the low-frequency variation of the baseline to detect events and uses a multiprocess method to accelerate the process of event detection. After the event is identified, its duration and amplitude information will be extracted and a resulting txt file will be generated for further analysis. Our software runs fast and can effectively extract the data from data of large-scale nanopore molecular translocation experiments.

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Source
http://dx.doi.org/10.1021/acs.langmuir.1c01597DOI Listing

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EasyNanopore: A Ready-to-Use Processing Software for Translocation Events in Nanopore Translocation Experiments.

Langmuir

August 2021

State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

Article Synopsis
  • EasyNanopore is a user-friendly software designed for analyzing nanopore molecular translocation experiments, available as an executable file for various operating systems.
  • The software utilizes an adaptive threshold to detect events and employs a multiprocess method to speed up detection.
  • Once events are identified, it extracts key data like duration and amplitude, generating a text file for further analysis, and is capable of handling large-scale experiments efficiently.*
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