AI Article Synopsis

  • The role of cellular apoptosis in managing M. tuberculosis during TB infection is still unclear.
  • Stutz et al. present strong evidence suggesting that apoptosis plays a crucial role in controlling M. tuberculosis infections in living organisms.
  • Additionally, compounds that promote apoptosis have been shown to restrict the growth of M. tuberculosis in mice models.

Article Abstract

The impact of cellular apoptosis in controlling M. tuberculosis during tuberculosis (TB) infection remains unresolved. In this issue of Immunity, Stutz et al. provide compelling evidence that apoptosis controls M. tuberculosis infection in vivo and compounds that induce apoptosis limit M. tuberculosis growth in mice.

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http://dx.doi.org/10.1016/j.immuni.2021.07.010DOI Listing

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