This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436376 | PMC |
| http://dx.doi.org/10.1093/cid/ciab695 | DOI Listing |
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